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Protein Overview: cat-4

General Information:
Name(s) found: cat-4 / CE05795 [WormBase]
Description(s) found:
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  • WBGene00000298 locus:cat-4 GTP cyclohydrolase 1 status:Confirmed UniProt:Q19980 protein_id:CAA96650.1 [WormBase]
  • pir||T21669 hypothetical protein F32G8.6 - Caenorhabditis elegans [NCBI NR]
  • gi|3876608|emb|CAA96650.1| C. elegans protein F32G8.6, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|2494697|sp|Q19980.1|GCH1_CAEEL RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase I; Short=GTP-CH-I [NCBI NR]
  • gi|17560486|ref|NP_505710.1| abnormal CATecholamine distribution family member (cat-4) [Caenorhabditis elegans] [NCBI NR]
  • GTP cyclohydrolase 1 OS=Caenorhabditis elegans GN=cat-4 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE05795 WBGene00000298 locus:cat-4 GTP cyclohydrolase I status:Partially_confirmed SW:Q19980 protein_id:CAA96650.1 [wormpep150.fasta]
  • 05795 WBGene00000298 locus:cat-4 GTP cyclohydrolase I status:Partially_confirmed SW:Q19980 protein_id:CAA96650.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • abnormal CATecholamine distribution CAT-4, GTP cyclohydrolase I (25.1 kD) (cat-4) [Caenorhabditis elegans]gi|3876608|emb|CAA96650.1| Hypothetical protein F32G8.6 [Caenorhabditis elegans]gi|7500359|pir||T21669 hypothetical protein F32G8.6 - Caenorhabditi [nrdb_11152004_Chlamydomonas]
  • GTP cyclohydrolase I status:Partially_confirmed SW:Q19980 protein_id:CAA96650.1 [wormpep115.fasta.reversed]
  • CE05795 GTP cyclohydrolase I status:Predicted SW:Q19980 protein_id:CAA96650.1 [wormpep80.hongbin]
  • CE05795 WBGene00000298 locus:cat-4 GTP cyclohydrolase I status:Partially_confirmed UniProt:Q19980 protein_id:CAA96650.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE05795 WBGene00000298 locus:cat-4 GTP cyclohydrolase I status:Partially_confirmed UniProt:Q19980 protein_id:CAA96650.1| [wormORF-contam.fasta]
  • GTP cyclohydrolase I (GTP-CH-I) [nr-271106-contam.fasta]
  • abnormal CATecholamine distribution family member (cat-4) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F32G8.6 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE05795 WBGene00000298 locus:cat-4 GTP cyclohydrolase I status:Confirmed UniProt:Q19980 protein_id:CAA96650.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE05795 WBGene00000298 locus:cat-4 status:Confirmed UniProt:Q19980 protein_id:CAA96650.1 GTP cyclohydrolase 1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 223 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: dopamine biosynthetic process [IMPLink to PubMed article]
    aromatic compound biosynthetic process [IEALink to PubMed article]
    Molecular Function: GTP cyclohydrolase I activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRIENESGF LSSDAASVGS EDDKVEMKKR NGTIPKEDHL KSMCNAYQSI IQHVGEDINR  60
   61 QGLLKTPERA AKAMMAFTKG YDDQLDELLN EAVFDEDHDE MVIVKDIEMF SLCEHHLVPF 120
  121 MGKVHIGYIP NKKVLGLSKL ARIVEMFSRR LQVQERLTKQ IATAMVQAVQ PSGVAVVIEA 180
  181 SHMCMVMRGV QKINASTTTS CMLGVFRDDP KTREEFLNLI NKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..223] PSI-BLAST 87.522879 GTP cyclohydrolase I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTP cyclohydrolase I activity
    		•  5.27071565931386 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  3.66553359909123 bayes_pls_golite062009
  • GTP cyclohydrolase activity
    		•  3.44912994722205 bayes_pls_golite062009
  • 6-pyruvoyltetrahydropterin synthase activity
    		•  2.94513271787536 bayes_pls_golite062009
  • catalytic activity
    		•  2.20788162511962 bayes_pls_golite062009
  • dihydroneopterin aldolase activity
    		•  1.96466418682643 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  1.73101699306211 bayes_pls_golite062009
  • binding
    		•  1.62520629128577 bayes_pls_golite062009
  • protein binding
    		•  1.34873192832825 bayes_pls_golite062009
  • hydrolase activity
    		•  1.10190985324326 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.974891318710762 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.25616855487144 bayes_pls_golite062009
  • urate oxidase activity
    		•  0.0294957696532921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle