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Catalysis of the reaction: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate. Catalysis of the breakage of a carbon-oxygen bond. Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 6-pyruvoyltetrahydropterin synthase activity
Acc: GO:0003874
Aspect: Molecular Function
Desc: Catalysis of the reaction: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate.
Synonyms:
  • 6-pyruvoyl tetrahydrobiopterin synthase activity
  • PTPS activity
  • 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)
  • 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003874 - 6-pyruvoyltetrahydropterin synthase activity (interactive image map)
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Created and Maintained by: Michael Riffle