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Protein Overview: prp-4

General Information:
Name(s) found: prp-4 / CE05372 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00007972 locus:prp-4 status:Partially_confirmed UniProt:Q93339 protein_id:CAB02270.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 496 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: RNA splicing [IEALink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    gastrulation with mouth forming first [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAENGNFAVP APPRQFGSLA NAESVNAILN AQQQNHGPTV SLERMEVSNQ ADSRHDAEMF  60
   61 AEFDRRRRAR TLTLPTDDVQ VKLKLRALNQ PICLFGEDAL DRRERLRALL STMSEDEIAA 120
  121 VLHTDEVNAD KADEETVTWY HRGPIELRMA RVSIADFSLR KAKLRLDKAR EEAARPAHEK 180
  181 ALARQEAHKW VQQINLHASQ VADTRPVAFC EFSADSEHIV TAGWSGSVAV WKREQCAQEI 240
  241 KFIGHSSQAG CARFHPGAFT QNDYSSLNVV SCSYDGTVLL WSLSQESPIG ELEQHPQRVS 300
  301 KVAFHPNGHH LATACFDSTW RMYDLTTKKE LLYQEGHSKS VADVAFHPDG SVALTGGHDC 360
  361 YGRVWDMRTG RCIMFLDGHT KEIHSVEWMP NGYEMITGSS DNSMKVWDLR MRRNTYTMPA 420
  421 HTSVVTRVRA DAAGQYLVSA SFDCTLKMWS TTGWQPLRQL QGHDTRILCV DISPDGQWMC 480
  481 SSAFDRTFKL WAQSDY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] MSA 1.232994 View MSA. No confident structure predictions are available.
    2 View Details [89..496] PSI-BLAST 88.69897 PAF-AH Holoenzyme: Lis1/Alfa2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • dynactin binding
    		•  7.11157019623125 bayes_pls_golite062009
    		• 6.67009948605948 bayes_pls_golite062009
  • GTPase activity
    		•  4.02994814377904 bayes_pls_golite062009
  • actin binding
    		•  3.86142918698875 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.85374902981345 bayes_pls_golite062009
  • RNA binding
    		•  3.77273677738815 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K4 specific)
    		•  3.53507344623686 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  3.00422709839505 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • dynein binding
    		•  2.54821997913979 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30918780727915 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.29049708962212 bayes_pls_golite062009
  • snoRNA binding
    		•  2.27164613239345 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • actin filament binding
    		•  2.0735069176589 bayes_pls_golite062009
  • DNA binding
    		•  1.71685536470455 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  1.63631972867316 bayes_pls_golite062009
  • acyltransferase activity
    		•  1.6301799051509 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  1.59523251984393 bayes_pls_golite062009
  • structural molecule activity
    		•  1.47097979074281 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.46155402212921 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.41752877005447 bayes_pls_golite062009
  • platelet-activating factor acetyltransferase activity
    		•  1.36229564654648 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  1.29381240188821 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • receptor activity
    		•  1.12819778129653 bayes_pls_golite062009
  • transcription factor activity
    		•  1.08768505897883 bayes_pls_golite062009
  • mRNA binding
    		•  1.05053985350578 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.01166033978052 bayes_pls_golite062009
  • myosin binding
    		•  0.989691178611801 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • signal transducer activity
    		•  0.974380908248463 bayes_pls_golite062009
  • protein transporter activity
    		•  0.964340340346761 bayes_pls_golite062009
  • angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • type 1 angiotensin receptor binding
    		•  0.920323565472959 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  0.848140419140051 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.707581908546932 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • insulin receptor binding
    		•  0.43316396073854 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.426429095658617 bayes_pls_golite062009
  • kinase activity
    		•  0.387572734234845 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  0.319410949467982 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.311523647180993 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.28606552120995 bayes_pls_golite062009
  • protein kinase activity
    		•  0.229242350006544 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.226335610368636 bayes_pls_golite062009
  • telomerase activity
    		•  0.18450996813475 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.161639372576406 bayes_pls_golite062009
  • myosin II binding
    		•  0.12060669039328 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • receptor binding
    		•  0.0390635451962911 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle