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Protein Overview: lin-39

General Information:
Name(s) found: lin-39 / CE03975 [WormBase]
Description(s) found:
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  • WBGene00003024 locus:lin-39 Homeobox protein lin-39 status:Confirmed UniProt:P34684 protein_id:CCD63594.1 [WormBase]
  • gi|71981493|ref|NP_001021164.1| abnormal cell LINeage family member (lin-39) [Caenorhabditis elegans] [NCBI NR]
  • gi|462537|sp|P34684.1|LIN39_CAEEL RecName: Full=Homeobox protein lin-39; AltName: Full=Abnormal cell lineage protein 39 [NCBI NR]
  • gi|304332|gb|AAC37168.1| homeobox protein [NCBI NR]
  • gi|304328|gb|AAB04137.1| homeobox protein [NCBI NR]
  • ref|NP_741228.1| abnormal cell LINeage LIN-39, C.Elegans Homeobox (27.8 kD) (lin-39) [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_498654.1| abnormal cell LINeage LIN-39, C.Elegans Homeobox (27.8 kD) (lin-39) [Caenorhabditis elegans] [NCBI NR]
  • gi|15150638|gb|AAK85445.1|AC006605_7 Abnormal cell lineage protein 39 [Caenorhabditis elegans] [NCBI NR]
  • Homeobox protein lin-39 OS=Caenorhabditis elegans GN=lin-39 PE=2 SV=1 [Swiss-Prot]
  • (P34684) Homeobox protein lin-39 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE03975 WBGene00003024 locus:lin-39 C. elegans homeobox gene lin-39 status:Confirmed SW:P34684 protein_id:AAK85445.1 [wormpep150.fasta]
  • 03975 WBGene00003024 locus:lin-39 C. elegans homeobox gene lin-39 status:Confirmed SW:P34684 protein_id:AAK85445.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • abnormal cell LINeage LIN-39, C.Elegans Homeobox (27.8 kD) (lin-39) [Caenorhabditis elegans]gi|17554218|ref|NP_498654.1| abnormal cell LINeage LIN-39, C.Elegans Homeobox (27.8 kD) (lin-39) [Caenorhabditis elegans]gi|15150638|gb|AAK85445.1| Abnormal cell [nrdb_11152004_Chlamydomonas]
  • locus:lin-39 C. elegans homeobox gene lin-39 status:Confirmed SW:P34684 protein_id:AAK85445.1 [wormpep115.fasta.reversed]
  • CE03975 locus:lin-39 C. elegans homeobox gene lin-39 status:Confirmed [wormpep80.hongbin]
  • CE03975 WBGene00003024 locus:lin-39 C. elegans homeobox gene lin-39 status:Confirmed UniProt:P34684 protein_id:AAK85445.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE03975 WBGene00003024 locus:lin-39 C. elegans homeobox gene lin-39 status:Confirmed UniProt:P34684 protein_id:AAK85445.1| [wormORF-contam.fasta]
  • Abnormal cell lineage protein 39 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Homeobox protein lin-39 (Abnormal cell lineage protein 39) [nr-271106-contam.fasta]
  • homeobox protein [nr-271106-contam.fasta]
  • abnormal cell LINeage family member (lin-39) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE03975 WBGene00003024 locus:lin-39 C. elegans homeobox gene lin-39 status:Confirmed UniProt:P34684 protein_id:CCD63594.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE03975 WBGene00003024 locus:lin-39 status:Confirmed UniProt:P34684 protein_id:CCD63594.1 Homeobox protein lin-39 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 253 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    Biological Process: negative regulation of vulval development [IMPLink to PubMed article]
    regulation of cell division [IMPLink to PubMed article]
    positive regulation of vulval development [IGILink to PubMed articleLink to PubMed article][IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    vulval development [IEPLink to PubMed article]
    regulation of cell fate specification [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    anterior/posterior pattern formation [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed article]
    Ras protein signal transduction [IEPLink to PubMed article]
    plasma membrane fusion [IMPLink to PubMed article]
    cell migration [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTSTSPSST DAPRATAPES SSSSSSSSSS SSSTSSVGAS GIPSSSELSS TIGYDPMTAS  60
   61 AALSAHFGSY YDPTSSSQIA SYFASSQGLG GPQYPILGDQ SLCYNPSVTS THHDWKHLEG 120
  121 DDDDDKDDDK KGISGDDDDM DKNSGGAVYP WMTRVHSTTG GSRGEKRQRT AYTRNQVLEL 180
  181 EKEFHTHKYL TRKRRIEVAH SLMLTERQVK IWFQNRRMKH KKENKDKPMT PPMMPFGANL 240
  241 PFGPFRFPLF NQF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] MSA 16.122996 View MSA. No confident structure predictions are available.
    2 View Details [148..253] PSI-BLAST 28.69897 DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  2.6809639302471 bayes_pls_golite062009
  • DNA binding
    		•  2.45264254102339 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.32767577674158 bayes_pls_golite062009
  • binding
    		•  2.12643314274039 bayes_pls_golite062009
  • transcription factor activity
    		•  1.9610710007594 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.71974400731667 bayes_pls_golite062009
  • protein binding
    		•  0.57484570028668 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.328460252819506 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.245215140763955 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0177888191364471 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.66

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle