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Protein Overview: CE03794

General Information:
Name(s) found: CE03794 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00002250 locus:lap-2 Putative aminopeptidase W07G4.4 status:Confirmed UniProt:Q27245 protein_id:CAB01448.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 522 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: protein metabolic process [IEALink to PubMed article]
    proteolysis [IEALink to PubMed article]
    Molecular Function: aminopeptidase activity [IEALink to PubMed article]
    manganese ion binding [IEALink to PubMed article]
    leucyl aminopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLQSLLSTK IVRATSIADA AFDAVVLVGS QDNVQQFGAI QQVSAIAPAV NNFLKLHSGA  60
   61 FNSTSLVQVD SSVVPSGRLI LSGTGNVSRD YDDVRRYQAA ARKGISMALS AGVKSPLLIT 120
  121 LPNSRFPNAE LVAALGALTP VYTPLNVREE ENKQKLNQLG LLAIGNSDTS ARLEKLVEAY 180
  181 DASFTVCRDV GEAGPERMAP PRVAEYIQGA FANGNIKVTV VDDQSVILKD FPLMAAVNRA 240
  241 ANCVKEHQAR LIRLEYVGEG ETQDTFFVVG KGVTIDTGGC DLKTGGHMFG MCRDKYGSAV 300
  301 VGGFFKAIDV LKPKNIKAVG YMCMVRNSIG SHAYTCDEVI TSRSGKRIHI YNTDAEGRLT 360
  361 MLDPLTLAKE EALNAKNPHL FTVATLTGHE VLSYGYYAAI MDNGPAKASG WARRVQNVGD 420
  421 EFGQPIEISR LHPEDFAFHM AECEQADLRQ GNTKPSVATL RGHQTPAAFL QMASRIDEHG 480
  481 TNSSHPLKYS HIDMGGCSGD HPSVSFPNPL VTLVAGLVLP HV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..522] PSI-BLAST 150.0 Leucine aminopeptidase, C-terminal domain; Leucine aminopeptidase (Aminopeptidase A), N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  3.26568153906254 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.98334117181651 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.06343447704714 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.5759162922092 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.891655769761122 bayes_pls_golite062009
  • binding
    		•  0.719625404193588 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  0.472688733072762 bayes_pls_golite062009
  • hydrolase activity
    		•  0.367195794753195 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  0.180859448845431 bayes_pls_golite062009
  • catalytic activity
    		•  0.168716604730246 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.0966237570696103 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle