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Protein Overview: spc7

General Information:
Name(s) found: spc7 / SPCC1020.02 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • kinetochore protein Spc7 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1364 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cell division site [IDALink to PubMed article]
    NMS complex [IDALink to PubMed article]
    spindle pole body [IDALink to PubMed article]
    condensed chromosome, centromeric region [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    inner kinetochore of condensed nuclear chromosome [IDALink to PubMed article]
    Biological Process: attachment of spindle microtubules to kinetochore [IGILink to PubMed article][IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    response to pheromone [IMPLink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    cell cycle [RCALink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    microtubule plus-end binding [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTSPRRNSI ATTDNVIGRN KSRKRPHSLG GPGALQELKE HTNPAKGILK SYSSFSVDPA  60
   61 FTGDEDFNDI HTQINNTVIG ISSNVMAASK RLQMEDLQQL SRETSRKSLN RRVSFASHAR 120
  121 VRWYPKDHQS DSEKSTSNHS TPERTFASDA KNHSPKGPTT TSFSRNETQS SPHSHSASII 180
  181 SDGSDMDIAS PIRSTESDMV SEALNAGHPP PSLYPENDDL SIQNPTKALP EAEKALDVHD 240
  241 ATREQVNDRE ETNMDLTIQF QEADSFLSHS ESIKGLSSSE QGTVYSLKAS HDPSNQTQLS 300
  301 SPNKSSSPTS IEISDFSKNN ENHDQSENKE EEEDMMLTRP IEIPQHFSPI ARPLTSQEAI 360
  361 VDMDITSNNI NLSPVSHFSN GLDLQNLEEA PMNLTRPINA NPHLTNHSPN DLTNGEEEMD 420
  421 TTSAFNIENS HLTLLSPIRP SSRSMEEQIM DLTQPISSTN APTHLNEDDL NQFTSNISSS 480
  481 SKPRKDNNKT ANSSKPIPDS EDFMDITRPF NILSPSKEAL SEEQPMELTS TVFPCENSTS 540
  541 HLEVEEAAMD ETVAFQIRGN NVELPSADKE NAEREEIPSY SDKSENFNTT SFTNHERSPN 600
  601 GNNNLKFSKD PNSSSPSRHV VATPTDKLGT RKRRLRYSTS SFDQSTLRRN RLATIRNARK 660
  661 SISTLNDREL LPVNFFEKKV NSGLYKSVER SENYRLGATP LTAEKPFTTE KPLSSLPEEV 720
  721 SRQPTDDKGE QVSNADVDSG LSKTERLTIQ QTNEIKHVPT NTTSSVKLPQ QPSNEDEKER 780
  781 ITTADYADST SLERLESQEP NRNELVQVGS SNAGNTTSVG MNEHEKSPVK LSKGVSNVDT 840
  841 SLGASTINTN ILNQDSGPNE EIPVGNEPEF DTMPTLPNVE PISLSDFLKM TGIEFLDNLT 900
  901 IAKRRETLLP NAEENKKCSI QELLESFYIQ FPLLELYKFS CQQLQDYIAE GKDFVTKIEE 960
  961 ETLKENPLLF YEYRKASSDM RVLMDSQFLM MKTFARLQAK GDWYEWREGL MQGIKHELNL1020
 1021 NLTGMQRSLT HLMDVANVIH PYAQEIQERY NGSITTVQTL KKQKEFANQY DSTLLAQAQE1080
 1081 KLEKLKVEVE RRRRLLSEKE ERRKELAIKI EQVTNSCSDL ELRTNAEQDF YAKNQDFEFD1140
 1141 EIKRYEEQLL NLKNELGWTI VSLTAGGIKL ATNNTALSPY SAEVTVEILR QNFQVNVDIA1200
 1201 CKFPNESNAC SSNVLEHVAS SFSKWHSKVF SRNLRLLKKY LNDVSICWEQ IVYLVQDFQR1260
 1261 LWYHWPFLSV ENDDKSIIIN VELYLRSVSS KVKVVFGLPI DTIYQTTEVG KFYASTSVAV1320
 1321 KQMYAESEGD SYVSEVLNTL SEVVHCTSTY ALSSACLTVW NKYS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run nuf2 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] MSA 1.201994 View MSA. No confident structure predictions are available.
    2 View Details [154..219] deduced N/A No confident structure predictions are available.
    3 View Details [220..401] MSA 3.218996 View MSA. No confident structure predictions are available.
    4 View Details [402..590] deduced N/A No confident structure predictions are available.
    5 View Details [591..740] deduced N/A No confident structure predictions are available.
    6 View Details [741..871] PSI-BLAST 15.09691 No description for 2dfsA was found.
    7 View Details [872..1364] PSI-BLAST 7.39794 Crystal Structure Analysis of ClpB

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7
    Term Confidence Notes
  • motor activity
    		•  2.79327761685782 bayes_pls_golite062009
  • microtubule motor activity
    		•  2.74365461017633 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.69246499202248 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.61582393123755 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.59641929642359 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.59333672868803 bayes_pls_golite062009
  • binding
    		•  2.44689197844883 bayes_pls_golite062009
  • transporter activity
    		•  2.17383908004663 bayes_pls_golite062009
  • ATPase activity
    		•  2.11122403732968 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.02444700826552 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.8908019270286 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.40488517180956 bayes_pls_golite062009
  • hydrolase activity
    		•  1.35268825531078 bayes_pls_golite062009
  • tubulin binding
    		•  0.979946830272106 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.97700154207756 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.93416103533555 bayes_pls_golite062009
  • microtubule binding
    		•  0.907162506177187 bayes_pls_golite062009
  • actin binding
    		•  0.883285269827407 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.725611289205392 bayes_pls_golite062009
  • nucleotide binding
    		•  0.717697610309727 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.713814218071151 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.713752628021599 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.608058786636536 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.5898258478934 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.574285918029279 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.40621909619333 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.399434758448606 bayes_pls_golite062009
  • GTP binding
    		•  0.398333597279278 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.39332178627529 bayes_pls_golite062009
  • kinetochore binding
    		•  0.308640501581731 bayes_pls_golite062009
  • DNA binding
    		•  0.259361683038035 bayes_pls_golite062009
  • ATP binding
    		•  0.19169045543599 bayes_pls_golite062009
  • protein transporter activity
    		•  0.178442534411253 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.165732470448462 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.162060759063149 bayes_pls_golite062009
  • dynein binding
    		•  0.150959629961177 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.114463153989353 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.10236059675512 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.081265446432119 bayes_pls_golite062009
  • protein binding
    		•  0.071010918255742 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.050107780790998 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle