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View Structure Prediction Details

Protein: spc7
Organism: Schizosaccharomyces pombe
Length: 1364 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for spc7.

Description E-value Query
Range
Subject
Range
gi|39592304, gi|... - gi|39592304|emb|CAE75525.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae], gi|187020927|em...
gi|157762282 - gi|157762282|ref|XP_001673483.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae AF16]
274.0 [0..1] [874..1049]
gi|50757613 - gi|50757613|ref|XP_415578.1| PREDICTED: similar to myosin heavy chain [Gallus gallus]
259.0 [0..768] [1360..1119]
gi|37930527, gi|... - gi|37930527|gb|AAP74661.1| elicitor-like transglutaminase M81 [Phytophthora infestans], gi|23505399|...
248.0 [0..3] [865..626]
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
245.0 [0..789] [1360..2183]
gi|33310026 - gi|33310026|gb|AAQ03243.1|AF414112_1 putative cell wall protein FLO11p [Candida albicans]
gi|68482880, gi|... - gi|68482880|ref|XP_714666.1| putative cell wall adhesin [Candida albicans SC5314], gi|46436253|gb|EA...
243.0 [0..9] [877..143]
gi|109113339 - gi|109113339|ref|XP_001118262.1| PREDICTED: myosin, heavy polypeptide 2, skeletal muscle, adult [Mac...
232.0 [0..839] [1360..993]

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Predicted Domain #1
Region A:
Residues: [1-153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTSPRRNSI ATTDNVIGRN KSRKRPHSLG GPGALQELKE HTNPAKGILK SYSSFSVDPA  60
   61 FTGDEDFNDI HTQINNTVIG ISSNVMAASK RLQMEDLQQL SRETSRKSLN RRVSFASHAR 120
  121 VRWYPKDHQS DSEKSTSNHS TPERTFASDA KNH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [154-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPKGPTTTSF SRNETQSSPH SHSASIISDG SDMDIASPIR STESDMVSEA LNAGHPPPSL  60
   61 YPENDD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [220-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSIQNPTKAL PEAEKALDVH DATREQVNDR EETNMDLTIQ FQEADSFLSH SESIKGLSSS  60
   61 EQGTVYSLKA SHDPSNQTQL SSPNKSSSPT SIEISDFSKN NENHDQSENK EEEEDMMLTR 120
  121 PIEIPQHFSP IARPLTSQEA IVDMDITSNN INLSPVSHFS NGLDLQNLEE APMNLTRPIN 180
  181 AN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [402-590]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHLTNHSPND LTNGEEEMDT TSAFNIENSH LTLLSPIRPS SRSMEEQIMD LTQPISSTNA  60
   61 PTHLNEDDLN QFTSNISSSS KPRKDNNKTA NSSKPIPDSE DFMDITRPFN ILSPSKEALS 120
  121 EEQPMELTST VFPCENSTSH LEVEEAAMDE TVAFQIRGNN VELPSADKEN AEREEIPSYS 180
  181 DKSENFNTT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [591-740]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFTNHERSPN GNNNLKFSKD PNSSSPSRHV VATPTDKLGT RKRRLRYSTS SFDQSTLRRN  60
   61 RLATIRNARK SISTLNDREL LPVNFFEKKV NSGLYKSVER SENYRLGATP LTAEKPFTTE 120
  121 KPLSSLPEEV SRQPTDDKGE QVSNADVDSG 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [741-871]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSKTERLTIQ QTNEIKHVPT NTTSSVKLPQ QPSNEDEKER ITTADYADST SLERLESQEP  60
   61 NRNELVQVGS SNAGNTTSVG MNEHEKSPVK LSKGVSNVDT SLGASTINTN ILNQDSGPNE 120
  121 EIPVGNEPEF D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.09691
Match: 2dfsA
Description: No description for 2dfsA was found.

Predicted Domain #7
Region A:
Residues: [872-1364]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TMPTLPNVEP ISLSDFLKMT GIEFLDNLTI AKRRETLLPN AEENKKCSIQ ELLESFYIQF  60
   61 PLLELYKFSC QQLQDYIAEG KDFVTKIEEE TLKENPLLFY EYRKASSDMR VLMDSQFLMM 120
  121 KTFARLQAKG DWYEWREGLM QGIKHELNLN LTGMQRSLTH LMDVANVIHP YAQEIQERYN 180
  181 GSITTVQTLK KQKEFANQYD STLLAQAQEK LEKLKVEVER RRRLLSEKEE RRKELAIKIE 240
  241 QVTNSCSDLE LRTNAEQDFY AKNQDFEFDE IKRYEEQLLN LKNELGWTIV SLTAGGIKLA 300
  301 TNNTALSPYS AEVTVEILRQ NFQVNVDIAC KFPNESNACS SNVLEHVASS FSKWHSKVFS 360
  361 RNLRLLKKYL NDVSICWEQI VYLVQDFQRL WYHWPFLSVE NDDKSIIINV ELYLRSVSSK 420
  421 VKVVFGLPID TIYQTTEVGK FYASTSVAVK QMYAESEGDS YVSEVLNTLS EVVHCTSTYA 480
  481 LSSACLTVWN KYS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.39794
Match: 1qvrA
Description: Crystal Structure Analysis of ClpB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
motor activity 2.79327761685782 bayes_pls_golite062009
microtubule motor activity 2.74365461017633 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.69246499202248 bayes_pls_golite062009
pyrophosphatase activity 2.61582393123755 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.59641929642359 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.59333672868803 bayes_pls_golite062009
binding 2.44689197844883 bayes_pls_golite062009
transporter activity 2.17383908004663 bayes_pls_golite062009
ATPase activity 2.11122403732968 bayes_pls_golite062009
transmembrane transporter activity 2.02444700826552 bayes_pls_golite062009
ATPase activity, coupled 1.8908019270286 bayes_pls_golite062009
cytoskeletal protein binding 1.40488517180956 bayes_pls_golite062009
hydrolase activity 1.35268825531078 bayes_pls_golite062009
tubulin binding 0.979946830272106 bayes_pls_golite062009
substrate-specific transporter activity 0.97700154207756 bayes_pls_golite062009
DNA-dependent ATPase activity 0.93416103533555 bayes_pls_golite062009
microtubule binding 0.907162506177187 bayes_pls_golite062009
actin binding 0.883285269827407 bayes_pls_golite062009
purine nucleotide binding 0.725611289205392 bayes_pls_golite062009
nucleotide binding 0.717697610309727 bayes_pls_golite062009
purine ribonucleotide binding 0.713814218071151 bayes_pls_golite062009
ribonucleotide binding 0.713752628021599 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.608058786636536 bayes_pls_golite062009
DNA helicase activity 0.5898258478934 bayes_pls_golite062009
nucleic acid binding 0.574285918029279 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.40621909619333 bayes_pls_golite062009
guanyl nucleotide binding 0.399434758448606 bayes_pls_golite062009
GTP binding 0.398333597279278 bayes_pls_golite062009
guanyl ribonucleotide binding 0.39332178627529 bayes_pls_golite062009
kinetochore binding 0.308640501581731 bayes_pls_golite062009
DNA binding 0.259361683038035 bayes_pls_golite062009
ATP binding 0.19169045543599 bayes_pls_golite062009
protein transporter activity 0.178442534411253 bayes_pls_golite062009
adenyl ribonucleotide binding 0.165732470448462 bayes_pls_golite062009
adenyl nucleotide binding 0.162060759063149 bayes_pls_golite062009
dynein binding 0.150959629961177 bayes_pls_golite062009
active transmembrane transporter activity 0.114463153989353 bayes_pls_golite062009
microfilament motor activity 0.10236059675512 bayes_pls_golite062009
ion transmembrane transporter activity 0.081265446432119 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
transcription regulator activity 0.050107780790998 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle