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Protein Overview: SPBC16A3.12c

General Information:
Name(s) found: SPBC16A3.12c [Sanger Pombe]
Description(s) found:
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  • pir||T39540 triglyceride lipase-cholesterol esterase - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|74676230|sp|P78898.2|TGCE2_SCHPO RecName: Full=Probable lipase C16A3.12c [NCBI NR]
  • gi|2842511|emb|CAA16863.1| triglyceride lipase-cholesterol esterase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113569|ref|NP_596777.1| triglyceride lipase-cholesterol esterase (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • triglyceride lipase-cholesterol esterase [Sanger Pombe]
  • Probable lipase C16A3.12c OS=Schizosaccharomyces pombe GN=SPBC16A3.12c PE=2 SV=2 [Swiss-Prot]
  • TRIGLYCERIDE LIPASE-CHOLESTEROL ESTERASE.: P78898; [pompepVF.fasta]
  • Putative triglyceride lipase-cholesterol esterase (EC 3.1.1.-) [pompep4896]
  • |||triglyceride lipase-cholesterol esterase [pompepnew.fasta]
  • SPBC16A3.12c protein [4896.FASTAC]
  • |||triglyceride lipase-cholesterol esterase (predicted)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • triglyceride lipase-cholesterol esterase. [Schizosaccharomyces pombe]gi|2842511|emb|CAA16863.1| SPBC16A3.12c [Schizosaccharomyces pombe]gi|7493524|pir||T39540 triglyceride lipase-cholesterol esterase - fission yeast (Schizosaccharomyces pombe) [nrdb_11152004_Chlamydomonas]
  • |||triglyceride lipase-cholesterol esterase |Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (P78898) Putative triglyceride lipase-cholesterol esterase (EC 3.1.1.-) [pompep4896_normal_reversed]
  • SPBC16A3.12c [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPBC16A3.12c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Probable lipase C16A3.12c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC16A3.12c PE=3 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 443 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    integral to membrane [IEA]
    fungal-type vacuole [IDALink to PubMed article]
    Biological Process: lipid metabolic process [ISSLink to PubMed article]
    cellular lipid catabolic process [ISS]
    sterol metabolic process [ISSLink to PubMed article]
    Molecular Function: lipase activity [ISSLink to PubMed article]
    sterol esterase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGFNKNQIY WGDYVGVIAA FVGVYTELVA RIFIYMIPER VREWFRVRII VLYHYYISSK  60
   61 TTDGMTDAVQ KCRNIYEICE AFGYRVEEHL VRTQDNFILC LHRITHPKQS QHKREVVYCH 120
  121 HGLMTNSELW VAVNESERSL PFVLIESGYD VWLGNNRGNK YSRKHITYKP KDEEFWNFSL 180
  181 DDMAMFDIPD TVDYILRETG REKLNYIGFS QGTAQAMAAL SINPDLNDKV NIFIGLAPAY 240
  241 APKGFSNYFV DYIVKVNPKI MYHLFGRRCL LPSVTFWQNI CYPPIFVKIV DVSLKILFNW 300
  301 DLSNISLNQK LCGYAHLYSF SSVKSVVHWL QIIKNCTFQL YDDDMALLAG YGSRHYQVPL 360
  361 FPTNNIKCPM LILWGGKDTL INMEVMRTAL PPHAKEVSIA HYEHLDFLWG QDVKEEVFPV 420
  421 VIDALKHHSL GKAKHFVKQN GFH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..443] PSI-BLAST 64.045757 Gastric lipase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  3.20549979663539 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  2.28093794718528 bayes_pls_golite062009
  • palmitoyl-(protein) hydrolase activity
    		•  2.14423515928317 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • triglyceride lipase activity
    		•  1.2959733599348 bayes_pls_golite062009
  • sterol esterase activity
    		•  1.21262745914703 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  1.18565704009692 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.985235528680562 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  0.92549140936125 bayes_pls_golite062009
  • peptidase activity
    		•  0.858311047004898 bayes_pls_golite062009
  • lipase activity
    		•  0.849473630399459 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.590445773074315 bayes_pls_golite062009
  • carboxylesterase activity
    		•  0.424330502936163 bayes_pls_golite062009
  • binding
    		•  0.351031277062254 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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