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View Structure Prediction Details

Protein: SPBC16A3.12c
Organism: Schizosaccharomyces pombe
Length: 443 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC16A3.12c.

Description E-value Query
Range
Subject
Range
gi|114631717 - gi|114631717|ref|XP_001138639.1| PREDICTED: lipase-like, ab-hydrolase domain containing 2 [Pan trogl...
269.0 [0..17] [428..89]
gi|149062728, gi... - gi|62642183|ref|XP_220067.3| PREDICTED: similar to lipase-like, ab-hydrolase domain containing 2 [Ra...
261.0 [0..43] [427..1]
gi|89033529 - gi|89033529|ref|XP_942300.1| PREDICTED: similar to lipase-like, ab-hydrolase domain containing 2 [Ho...
260.0 [0..43] [428..1]
LIPK_MOUSE - Lipase member K OS=Mus musculus GN=Lipk PE=2 SV=1
260.0 [0..44] [427..3]
gi|73996079 - gi|73996079|ref|XP_853107.1| PREDICTED: similar to lipase A precursor [Canis familiaris]
253.0 [0..28] [429..4]

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Predicted Domain #1
Region A:
Residues: [1-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGFNKNQIY WGDYVGVIAA FVGVYTELVA RIFIYMIPER VREWFRVRII VLYHYYISSK  60
   61 TTDGMTDAVQ KCRNIYEICE AFGYRVEEHL VRTQDNFILC LHRITHPKQS QHKREVVYCH 120
  121 HGLMTNSELW VAVNESERSL PFVLIESGYD VWLGNNRGNK YSRKHITYKP KDEEFWNFSL 180
  181 DDMAMFDIPD TVDYILRETG REKLNYIGFS QGTAQAMAAL SINPDLNDKV NIFIGLAPAY 240
  241 APKGFSNYFV DYIVKVNPKI MYHLFGRRCL LPSVTFWQNI CYPPIFVKIV DVSLKILFNW 300
  301 DLSNISLNQK LCGYAHLYSF SSVKSVVHWL QIIKNCTFQL YDDDMALLAG YGSRHYQVPL 360
  361 FPTNNIKCPM LILWGGKDTL INMEVMRTAL PPHAKEVSIA HYEHLDFLWG QDVKEEVFPV 420
  421 VIDALKHHSL GKAKHFVKQN GFH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.045757
Match: 1hlgA
Description: Gastric lipase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 3.20549979663539 bayes_pls_golite062009
malate dehydrogenase activity 2.28093794718528 bayes_pls_golite062009
palmitoyl-(protein) hydrolase activity 2.14423515928317 bayes_pls_golite062009
catalytic activity 1.39629727416851 bayes_pls_golite062009
triglyceride lipase activity 1.2959733599348 bayes_pls_golite062009
sterol esterase activity 1.21262745914703 bayes_pls_golite062009
thiolester hydrolase activity 1.18565704009692 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.985235528680562 bayes_pls_golite062009
palmitoyl-CoA hydrolase activity 0.92549140936125 bayes_pls_golite062009
peptidase activity 0.858311047004898 bayes_pls_golite062009
lipase activity 0.849473630399459 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.590445773074315 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009
binding 0.351031277062254 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle