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Protein Overview: erg27

General Information:
Name(s) found: erg27 / SPBC1709.07 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • 3-keto sterol reductase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 338 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [ISSLink to PubMed article]
    Biological Process: ergosterol biosynthetic process [ISSLink to PubMed article]
    Molecular Function: 3-keto sterol reductase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFRKYALIT GSNSGLGFGI ATRLLQFYQP RLQDEPEVFT VILTCRSREK AEDACRRLKE  60
   61 FFPDRKIRLE YVLLDLSNMA SVEAAVQDIA TRFPKLDFVY LNAGAWDLEG IQWLKAIFST 120
  121 LINPIQALTH PTFYKETAGR VSNDSLGYIF ESNVFGHFYL KNRLAELKVL RSSTKVVLTS 180
  181 SLVAEKKSLD FEDLQCFHGE QPYQSSKRLL DVLHYAELEK GLPFEQYLVH PGLCTTNMYE 240
  241 TFLGPILVMC AKLGFYICRL LGSPWHTISP YVAAFAFLWT ALHATKEDQS IKWGAAVTRF 300
  301 GHERVLSTPV ELILPSEQEK ALEYMTKLYQ EWKKKLVS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..338] PSI-BLAST 47.69897 Crystal structure of peroxisomal trans 2-enoyl CoA reductase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • steroid dehydrogenase activity
    		•  3.70115036051018 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  3.56748749904419 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.27417613545298 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.97774592602866 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
    		•  1.03845584151228 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  0.744959961067911 bayes_pls_golite062009
  • signal transducer activity
    		•  0.620476349006324 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.620476349006324 bayes_pls_golite062009
  • binding
    		•  0.553666136934364 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  0.48259320361048 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.39101464838432 bayes_pls_golite062009
  • receptor activity
    		•  0.0485610523889735 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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