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Protein Overview: ogm2

General Information:
Name(s) found: ogm2 / SPAPB1E7.09 [Sanger Pombe]
Description(s) found:
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  • gi|74638359|sp|Q9C100.1|PMT2_SCHPO RecName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 2 [NCBI NR]
  • gi|19115047|ref|NP_594135.1| protein O-mannosyltransferase Ogm2 [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|13624764|emb|CAC36926.1| protein O-mannosyltransferase Ogm2 [Schizosaccharomyces pombe] [NCBI NR]
  • protein O-mannosyltransferase Ogm2 [Sanger Pombe]
  • Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Schizosaccharomyces pombe GN=ogm2 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE MANNOSYLTRANSFERASE; DOLICHYL PHOSPHATE- D-MANNOSE-PROTEIN O-D-MANNOSYLTRANSFERASE; INVOLVED IN INITIATION OF O-GLYCOSYLATION; BY SIMILARITY TO S. CEREVISIAE PMT GENES: Q9C100; [pompepVF.fasta]
  • PUTATIVE MANNOSYLTRANSFERASE; DOLICHYL PHOSPHATE-D-MANNOSE-PROTEIN O-D-MANNOSYLTRANSFERASE; INVOLVED IN INITIATION OF O-GLYCOSYLATION; BY SISMILARITY TO S. CEREVISIAE PMT GENES: Q9C100; [pompepV13]
  • Putative mannosyltransferase, dolichyl phosphate-D-mannose-protein O-D-mannosyltransferase, involved in initiation of O-glycosylation, by sismilarity to S. cerevisiae PMT genes [pompep4896]
  • |||glycosyl transferase family 39 [pompepnew.fasta]
  • SPAPB1E7.09 protein [4896.FASTAC]
  • |||glycosyl transferase family 39|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative Mannosyltransferase; dolichyl phosphate-D-mannose-protein O-D-mannosyltransferase; involved in initiation of O-glycosylation; by sismilarity to S. cerevisiae PMT genes [Schizosaccharomyces pombe]gi|13624764|emb|CAC36926.1| SPAPB1E7.09 [Schizosac [nrdb_11152004_Chlamydomonas]
  • (Q9C100) Putative mannosyltransferase, dolichyl phosphate-D-mannose-protein O-D-mannosyltransferase, involved in initiation of O-glycosylation, by sismilarity to S. cerevisiae PMT genes [pompep4896_normal_reversed]
  • |ogm2|oma2|protein O-mannosyltransferase Ogm2|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Dolichyl-phosphate-mannose--protein mannosyltransferase 2 [nr-271106-contam.fasta]
  • SPAPB1E7.09 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAPB1E7.09 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ogm2 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 739 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [IDALink to PubMed article]
    nuclear membrane [IDALink to PubMed article]
    integral to membrane [IEA]
    endomembrane system [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    dolichyl-phosphate-mannose-protein mannosyltransferase complex [IDALink to PubMed article]
    Biological Process: protein amino acid O-linked mannosylation [TASLink to PubMed article]
    Molecular Function: protein heterodimerization activity [IPILink to PubMed article]
    dolichyl-phosphate-mannose-protein mannosyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYEQLHAQS GQLRQRFPSK HSEIEDEVAN EKEELKDATK SALGEVKTNK KYYILGYFLV  60
   61 PLLLTVIAGF VRVWKIADSN VVIWDEAHFG KFASYYLKHE FYFDVHPPLG KMLNAVAGKL 120
  121 VGYDGSFDFS SGATYPEDLN YKFMRLWNAA FGTLCIPLVY FTALNFNYSF LAATLCTLMV 180
  181 ALDNHLATIS RFILLDSMLL FFIISTFFCL SRYHVYHKAP FTFYWFKWLF LTGVCIGCVC 240
  241 SVKLVGLFIT AVVGLYTVDE LWCLLNDKRV TWKAYAGHWI ARVCLLIFLP ILIYAFTFWI 300
  301 QFAVLYRSGP GDAQMPSLFQ ARLEGSPLTK NPIDLMYGSK FTLKSRNPTG ALLHSHVQTY 360
  361 PEGSEQQQVT GYHHKDGNNE WMFVPTHGVA YNYEENDPMN PILNGSVVRL IHPFTNRNLH 420
  421 THKIPAPLNK RMYEVSGYGL GDVGDEKDYW IVNILYDTAH RDAYNVRSLS TVFQLYNPVV 480
  481 GCYLSSSSSS LPSWGFGQIE MYCDPDPDPS NTDTQWNVEE HINPRLPEGS INDYPSSFWS 540
  541 DFLHLNRAML RANNGLIPDE DKLDALRSEA YQWPFLLATL RMCGWGDNQI KYLLVGNPVA 600
  601 YWFATSSLIV FALFVVGAVL AWRRRVLRWS QEACDTFHYA GIYPFLGWFF NYLPYYIMGR 660
  661 VLYVHHYEPS YALSTFTAAF VVDWFTKKMP KIVRVVVFIS LYAIIAGVFI YFKDVTFGMH 720
  721 GPASDFHRLR WLNSWNVHD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..125] deduced N/A No confident structure predictions are available.
    2 View Details [126..325] MSA 2.046995 View MSA. No confident structure predictions are available.
    3 View Details [326..532] PSI-BLAST 52.0 Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function
    4 View Details [533..634] MSA 1.093991 View MSA. No confident structure predictions are available.
    5 View Details [635..739] MSA 2.091988 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • dolichyl-phosphate-mannose-protein mannosyltransferase activity
    		•  7.33543412640964 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  6.32966341675541 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  2.60661923349025 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.57555885876017 bayes_pls_golite062009
  • receptor activity
    		•  1.99332745476324 bayes_pls_golite062009
  • binding
    		•  1.86366637427031 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.71523634580131 bayes_pls_golite062009
  • signal transducer activity
    		•  1.71523634580131 bayes_pls_golite062009
  • cation channel activity
    		•  1.66500687404195 bayes_pls_golite062009
  • ion channel activity
    		•  1.61859406934521 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  1.57127083095499 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  1.55374970486978 bayes_pls_golite062009
  • channel activity
    		•  1.55374970486978 bayes_pls_golite062009
  • inositol-1,4,5-trisphosphate receptor activity
    		•  1.28298370923705 bayes_pls_golite062009
  • transferase activity
    		•  0.981084601370981 bayes_pls_golite062009
  • calcium channel activity
    		•  0.85901349040585 bayes_pls_golite062009
  • catalytic activity
    		•  0.659936859803906 bayes_pls_golite062009
  • calcium-release channel activity
    		•  0.65133561512386 bayes_pls_golite062009
  • gated channel activity
    		•  0.53737429019655 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.52162184692236 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.52162184692236 bayes_pls_golite062009
  • protein binding
    		•  0.405144403982597 bayes_pls_golite062009
  • inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
    		•  0.152598505509111 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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