YRC Public Data Repository - Protein Structure Prediction

Protein:	ogm2
Organism:	Schizosaccharomyces pombe
Length:	739 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ogm2.

Description	E-value	Query Range	Subject Range
gi\|14625800 - gi\|14625800\|gb\|AAK71510.1\| dolichyl-phosphate-mannose:protein mannosyltransferase [Emericella nidula... gi\|49095562, gi\|... - gi\|67537870\|ref\|XP_662709.1\| hypothetical protein AN5105.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	727.0	[0..14]	[739..19]
gi\|15011522 - gi\|15011522\|gb\|AAK77607.1\|AF396953_1 protein O-mannosyl transferase [Aspergillus awamori]	723.0	[0..2]	[739..8]
gi\|32415215, gi\|... - gi\|9368945\|emb\|CAB99175.1\| probable dolichyl-phosphate-mannose--protein mannosyltransferase [Neurosp... gi\|85079003 - gi\|85079003\|ref\|XP_956270.1\| probable dolichyl-phosphate-mannose--protein mannosyltransferase [MIPS]...	721.0	[0..14]	[739..25]
gi\|46109306, gi\|... - gi\|46109306\|ref\|XP_381711.1\| hypothetical protein FG01535.1 [Gibberella zeae PH-1], gi\|42545318\|gb\|E...	720.0	[0..4]	[739..11]
gi\|90307565, gi\|... - gi\|90307565\|gb\|EAS37196.1\| hypothetical protein CIMG_02550 [Coccidioides immitis RS], gi\|119196351\|r...	718.0	[0..7]	[739..12]
gi\|83770978 - gi\|83770978\|dbj\|BAE61111.1\| unnamed protein product [Aspergillus oryzae] gi\|169764100 - gi\|169764100\|ref\|XP_001727950.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|220698672, gi... - gi\|238490093\|ref\|XP_002376284.1\| protein O-mannosyl transferase [Aspergillus flavus NRRL3357], gi\|22...	704.0	[0..2]	[739..6]
gi\|48479770 - gi\|48479770\|gb\|AAT44966.1\| protein O-mannosyltransferase 2 [Aspergillus fumigatus]	703.0	[0..1]	[739..1]
gi\|159130988 - gi\|159130988\|gb\|EDP56101.1\| protein O-mannosyl transferase [Aspergillus fumigatus A1163] gi\|70991332, gi\|... - gi\|70991332\|ref\|XP_750515.1\| protein O-mannosyl transferase [Aspergillus fumigatus Af293], gi\|668481...	692.0	[0..54]	[739..74]
gi\|169596911, gi... - gi\|169596911\|ref\|XP_001791879.1\| hypothetical protein SNOG_01229 [Phaeosphaeria nodorum SN15], gi\|11...	691.0	[0..4]	[739..8]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYEQLHAQS GQLRQRFPSK HSEIEDEVAN EKEELKDATK SALGEVKTNK KYYILGYFLV  60
   61 PLLLTVIAGF VRVWKIADSN VVIWDEAHFG KFASYYLKHE FYFDVHPPLG KMLNAVAGKL 120
  121 VGYDG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [126-325]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFDFSSGATY PEDLNYKFMR LWNAAFGTLC IPLVYFTALN FNYSFLAATL CTLMVALDNH  60
   61 LATISRFILL DSMLLFFIIS TFFCLSRYHV YHKAPFTFYW FKWLFLTGVC IGCVCSVKLV 120
  121 GLFITAVVGL YTVDELWCLL NDKRVTWKAY AGHWIARVCL LIFLPILIYA FTFWIQFAVL 180
  181 YRSGPGDAQM PSLFQARLEG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [326-532]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPLTKNPIDL MYGSKFTLKS RNPTGALLHS HVQTYPEGSE QQQVTGYHHK DGNNEWMFVP  60
   61 THGVAYNYEE NDPMNPILNG SVVRLIHPFT NRNLHTHKIP APLNKRMYEV SGYGLGDVGD 120
  121 EKDYWIVNIL YDTAHRDAYN VRSLSTVFQL YNPVVGCYLS SSSSSLPSWG FGQIEMYCDP 180
  181 DPDPSNTDTQ WNVEEHINPR LPEGSIN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.0
Match:	1t9fA
Description:	Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dolichyl-phosphate-mannose-protein mannosyltransferase activity	7.33543412640964	bayes_pls_golite062009
mannosyltransferase activity	6.32966341675541	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.60661923349025	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.57555885876017	bayes_pls_golite062009
receptor activity	1.99332745476324	bayes_pls_golite062009
binding	1.86366637427031	bayes_pls_golite062009
molecular transducer activity	1.71523634580131	bayes_pls_golite062009
signal transducer activity	1.71523634580131	bayes_pls_golite062009
cation channel activity	1.66500687404195	bayes_pls_golite062009
ion channel activity	1.61859406934521	bayes_pls_golite062009
substrate-specific channel activity	1.57127083095499	bayes_pls_golite062009
passive transmembrane transporter activity	1.55374970486978	bayes_pls_golite062009
channel activity	1.55374970486978	bayes_pls_golite062009
inositol-1,4,5-trisphosphate receptor activity	1.28298370923705	bayes_pls_golite062009
transferase activity	0.981084601370981	bayes_pls_golite062009
calcium channel activity	0.85901349040585	bayes_pls_golite062009
catalytic activity	0.659936859803906	bayes_pls_golite062009
calcium-release channel activity	0.65133561512386	bayes_pls_golite062009
gated channel activity	0.53737429019655	bayes_pls_golite062009
ligand-gated ion channel activity	0.52162184692236	bayes_pls_golite062009
ligand-gated channel activity	0.52162184692236	bayes_pls_golite062009
protein binding	0.405144403982597	bayes_pls_golite062009
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	0.152598505509111	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [533-634]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYPSSFWSDF LHLNRAMLRA NNGLIPDEDK LDALRSEAYQ WPFLLATLRM CGWGDNQIKY  60
   61 LLVGNPVAYW FATSSLIVFA LFVVGAVLAW RRRVLRWSQE AC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [635-739]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTFHYAGIYP FLGWFFNYLP YYIMGRVLYV HHYEPSYALS TFTAAFVVDW FTKKMPKIVR  60
   61 VVVFISLYAI IAGVFIYFKD VTFGMHGPAS DFHRLRWLNS WNVHD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: