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Protein Overview: SPAC19A8.03

General Information:
Name(s) found: SPAC19A8.03 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • phosphatidylinositol-3-phosphatase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 559 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article][ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: vesicle-mediated transport [ISSLink to PubMed article]
    phosphatidylinositol metabolic process [IC]
    inositol lipid-mediated signaling [ISSLink to PubMed article]
    phosphoinositide dephosphorylation [ISSLink to PubMed article]
    Molecular Function: phosphoprotein phosphatase activity [IEA]
    phosphatidylinositol-3-phosphatase activity [ISSLink to PubMed article]
    phosphatase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENIKVAKVG NVKFVNKGNE LNGTLHLTAY HSIFSISENG KEIWTAYSMI NNVKLCSNEK  60
   61 SFCIRIQCRD FMFFCWRFQS TEDAMDVYDT LQELMSINSI NMLYAFYYMP SGDEEKLPSS 120
  121 WKSFLLENEY RRMGVGDSTQ ADGAGGNWRI TKINENYSEC HSYPQALAVP ASISDSVIYY 180
  181 GCKYRSKNRF PTLTYLHKNS FSITRASQPL VGIRQNRSAQ DEKLVEAIFA TSIIPGKENL 240
  241 IVDARPSTNA MANIAVGAGS ENMDHYRFAK KIYLGIDNIH VMRDSLNKIV NALKNTDISA 300
  301 APPLIELLNR SSWLKHLANI LQGAVLIVKT VHFRHAHVLV HCSDGWDRTS QLCALPQLCL 360
  361 DPYYRTIEGF FALVEKDWLS FGHRFAERCC HLPGKRIFTI DSSYSEEPPQ SSPSSTLQYT 420
  421 FSTVRSALSG FSIDHSEKMM SPVFHQFLDC VWQIMDQFPN CFEFNERFLR RLLYHLYSCQ 480
  481 YGSFLYNSER ERAQASVSTH TRCIWDYFLS RKDEFKNPNY VPYDDVIMPD PSSLRWWSAS 540
  541 FAQPDENMNI PSPSESPSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..559] PSI-BLAST 1000.0 Crystal Structure of Myotubularin-related protein 2 complexed with phosphate

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.30669036331612 bayes_pls_golite062009
  • phosphatase activity
    		•  7.03758345564381 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.82821455971597 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.83769298632658 bayes_pls_golite062009
  • protein tyrosine phosphatase activity
    		•  5.3097342170423 bayes_pls_golite062009
  • lipid phosphatase activity
    		•  4.03975183132282 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine phosphatase activity
    		•  2.94635032478625 bayes_pls_golite062009
  • transmembrane receptor protein phosphatase activity
    		•  2.94635032478625 bayes_pls_golite062009
  • protein tyrosine/serine/threonine phosphatase activity
    		•  2.77531895423367 bayes_pls_golite062009
  • phosphatidylinositol-3-phosphatase activity
    		•  2.60529675907066 bayes_pls_golite062009
  • phosphatidylinositol trisphosphate phosphatase activity
    		•  2.05577133553311 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  1.95004535887255 bayes_pls_golite062009
  • phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
    		•  1.72084618199574 bayes_pls_golite062009
  • hydrolase activity
    		•  1.64178855997223 bayes_pls_golite062009
  • phosphatidylinositol bisphosphate phosphatase activity
    		•  1.51576958903553 bayes_pls_golite062009
  • binding
    		•  1.42026750513729 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  1.1200449509328 bayes_pls_golite062009
  • protein binding
    		•  1.07441758584517 bayes_pls_golite062009
  • catalytic activity
    		•  1.06283028154109 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine phosphatase activity
    		•  0.724257798127697 bayes_pls_golite062009
  • kinase activity
    		•  0.541255358115631 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.532875179381704 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.359793029026564 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.355387992614734 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.335498703113274 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.291525352733402 bayes_pls_golite062009
  • receptor activity
    		•  0.191946218805025 bayes_pls_golite062009
  • transferase activity
    		•  0.0332461821062801 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle