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Protein Overview: sap62

General Information:
Name(s) found: sap62 / SPBC21C3.05 [Sanger Pombe]
Description(s) found:
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  • gi|74698336|sp|Q9P7L8.1|SAP62_SCHPO RecName: Full=CWF complex protein sap62; AltName: Full=U2 snRNP-associated protein sap62 [NCBI NR]
  • gi|7106070|emb|CAB76041.1| zinc finger protein Sap62 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113377|ref|NP_596585.1| zinc finger protein Sap62 [Schizosaccharomyces pombe] [NCBI NR]
  • pir||T50349 homolog to Mouse SF3A spliceosome complex protein SAP62 [imported] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • zinc finger protein Sap62 [Sanger Pombe]
  • CWF complex protein sap62 OS=Schizosaccharomyces pombe GN=sap62 PE=1 SV=1 [Swiss-Prot]
  • PUTATIVE PRE-MRNA SPLICING FACTOR; SIMILAR TO S. CEREVISIAE PRP11: Q9P7L8; [pompepVF.fasta]
  • Similar to mouse SF3A spliceosome complex protein SAP62 [pompep4896]
  • |sap62||putative pre-mRNA splicing factor [pompepnew.fasta]
  • SPBC21C3.05 protein (Sap62 protein) [4896.FASTAC]
  • |sap62||localization spliceosome complex|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • similar to Mouse SF3A spliceosome complex protein SAP62 [Schizosaccharomyces pombe]gi|7106070|emb|CAB76041.1| SPBC21C3.05 [Schizosaccharomyces pombe]gi|11359059|pir||T50349 homolog to Mouse SF3A spliceosome complex protein SAP62 [imported] - fission yea [nrdb_11152004_Chlamydomonas]
  • (Q9P7L8) Similar to mouse SF3A spliceosome complex protein SAP62 [pompep4896_normal_reversed]
  • |sap62||zinc finger protein Sap62|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPBC21C3.05 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC21C3.05 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Pre-mRNA-splicing factor sap62 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sap62 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 217 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    spliceosomal complex [RCALink to PubMed article]
    U2 snRNP [ISSLink to PubMed article]
    Biological Process: spliceosome assembly [ISSLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    RNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYQNRAGVR FGGGGVAGYQ ETNAARRERL RKLALETIDL SKDPYLMKNH LGTFECRLCL  60
   61 TTHANENSYL THTQGKKHQT NLARRQALEN KKSQENAPQV LLGISQSHVQ VKKSVVKIGR 120
  121 PGYKVSKIRE AESGKFGLRF QIKYPDIEVN AKPRYRIMSA YEQRVEAPDR KFQYLVVAAE 180
  181 PYESIAFKID RAPGKFWSYW DAPTYTIQFF YNLTKIS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] FFAS03 1.83 Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
    2 View Details [145..217] MSA 1.02698 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.37529385176635 bayes_pls_golite062009
  • DNA binding
    		•  3.3049326844117 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.24981360535232 bayes_pls_golite062009
  • snRNA binding
    		•  3.16782731106334 bayes_pls_golite062009
  • RNA binding
    		•  3.11293528368816 bayes_pls_golite062009
  • U1 snRNA binding
    		•  2.86343975521155 bayes_pls_golite062009
  • binding
    		•  2.84954567129719 bayes_pls_golite062009
  • transcription factor activity
    		•  2.44389510173662 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.57041104288348 bayes_pls_golite062009
  • mRNA binding
    		•  1.28525296322454 bayes_pls_golite062009
  • transcription activator activity
    		•  1.20323819132961 bayes_pls_golite062009
  • protein binding
    		•  0.975412203442928 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.732558534458316 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.686318575498149 bayes_pls_golite062009
  • chromatin binding
    		•  0.626365497850853 bayes_pls_golite062009
  • transcription factor binding
    		•  0.515821187939278 bayes_pls_golite062009
  • catalytic activity
    		•  0.263007611601737 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.200483461579207 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.113925660147477 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0855506955761403 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle