Protein Overview: SPAC57A10.09c

General Information:
Name(s) found:	SPAC57A10.09c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T38936 non-histone chromosomal protein high mobility group - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|74627097\|sp\|P87057.1\|NHP6_SCHPO RecName: Full=Non-histone chromosomal protein 6 [NCBI NR] gi\|2058376\|emb\|CAB08172.1\| High-mobility group non-histone chromatin protein [Schizosaccharomyces pombe] [NCBI NR] gi\|19114226\|ref\|NP_593314.1\| High-mobility group non-histone chromatin protein [Schizosaccharomyces pombe] [NCBI NR] High-mobility group non-histone chromatin protein [Sanger Pombe] Non-histone chromosomal protein 6 OS=Schizosaccharomyces pombe GN=nhp6 PE=2 SV=1 [Swiss-Prot] NONHISTONE CHROMOSOMAL PROTEIN; CONTAINS HMG BOX; INVOLVED IN ESTABLISHMENT OR MAINTENENCE OF CHROMATIN ARCHITECTURE; INVOLVED IN TRANSCRIPTIONAL REGULATION FROM POLII PROMOTER; SIMILAR TO S. CEREVISIAE NHP6B: P87057; [pompepVF.fasta] NONHISTONE CHROMOSOMAL PROTEIN 6B: P87057; [pompepV13] Nonhistone chromosomal protein [pompep4896] \|\|\|nonhistone chromosomal protein [pompepnew.fasta] SPAC57A10.09c protein [4896.FASTAC] \|\|\|HMG box\|Schizosaccharomyces pombe\|chr 1\|\|\|Manual [pombe041504.fasta] nonhistone chromosomal protein; contains HMG box; involved in establishment or maintenence of chromatin architecture; involved in transcriptional regulation from PolII promoter;FT similar to S. cerevisiae NHP6B [Schizosaccharomyces pombe]gi\|2058376\|emb\|C [nrdb_11152004_Chlamydomonas] (P87057) Nonhistone chromosomal protein [pompep4896_normal_reversed] \|nhp6\|\|High-mobility group non-histone chromatin protein\|Schizosaccharomyces pombe\|chr 1\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] SPAC57A10.09c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] Nonhistone chromosomal protein 6 [nr-271106-contam.fasta] hypothetical protein SPAC57A10.09c [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] \|nhp6\|\|High-mobility group non-histone chromatin protein \|Schizosaccharomyces pombe\|chr 1\|\|\|Manual [Other_S_Pombe_12-15-2011_reversed.fasta] Non-histone chromosomal protein 6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nhp6 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	108 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] nuclear chromatin [ISS] cytosol [IDA]
Biological Process:	chromatin remodeling [ISS] cellular response to stress [IEP] positive regulation of transcription from RNA polymerase II promoter [ISS] regulation of transcription from RNA polymerase III promoter [ISS] nucleosome assembly [ISS] regulation of transcription from RNA polymerase II promoter [ISS]
Molecular Function:	DNA binding [ISS] transcription regulator activity [NAS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MPRAAKSSRK KDPNTPKRNM SAFMFFSIEN REKMKTDNPD ATFGQLGSLL GKRWKELTST 60 61 EREPYEEKAR QDKERYERER KEYDTKLANG EKTGKASAPA AAAAAKEE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..108]	PSI-BLAST	20.09691	No description for 2gzkA was found.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
DNA binding	5.15324651287773	bayes_pls_golite062009
nucleic acid binding	5.01228762819617	bayes_pls_golite062009
transcription regulator activity	4.9607192917135	bayes_pls_golite062009
sequence-specific DNA binding	4.06355503548774	bayes_pls_golite062009
transcription factor activity	3.82658263870186	bayes_pls_golite062009
binding	3.6211482127468	bayes_pls_golite062009
transcription activator activity	2.95665802871704	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.75319687398598	bayes_pls_golite062009
protein binding	2.18211240370246	bayes_pls_golite062009
chromatin binding	1.64428658020027	bayes_pls_golite062009
transcription repressor activity	1.53825678633232	bayes_pls_golite062009
transcription factor binding	1.10315330167937	bayes_pls_golite062009
DNA bending activity	0.87985209274756	bayes_pls_golite062009
crossed form four-way junction DNA binding	0.293183929205961	bayes_pls_golite062009
bent DNA binding	0.293183929205961	bayes_pls_golite062009
open form four-way junction DNA binding	0.293183929205961	bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding	0.261169200304829	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle