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Protein Overview: pdf1

General Information:
Name(s) found: pdf1 / SPBC530.12c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • palmitoyl protein thioesterase-dolichol pyrophosphate phosphatase fusion 1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 603 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [ISSLink to PubMed article]
    integral to membrane [IEA]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: protein depalmitoylation [IC]
    vacuolar acidification [IGILink to PubMed article]
    regulation of pH [IMPLink to PubMed article]
    sphingolipid biosynthetic process [ISSLink to PubMed article]
    Molecular Function: palmitoyl-(protein) hydrolase activity [ISSLink to PubMed article]
    dolichyldiphosphatase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSFAIPIIS LDKVRLAIND GASEQLPVVI WHGLGDTPTS FTLTEVSQRV QKLTKGAVYA  60
   61 IRVGDNEFED IKAGYLGKLE DQLDEVCDLI GNEDSLSNGF YALGLSQGGL FLRALAQTCD 120
  121 AAKIRSLITL GSPHSGINTI PGCSPTNLIC KAVVHSILGL GIWHSWIQNH VVQAQYYRTE 180
  181 KQYDKYLENN KFLTHLNNEV LHDNYTRNIE KLKELDNLVA VSFERDDIVE PPYSTGFGWI 240
  241 NETTGENIEM EDFVLYESLG LKDLVNQGKL ETISFPGRHL QMRWGDFDAL VLKYFKDEKE 300
  301 EKTELEESTR PSNFLSTYFV SPLVSAIDGT VDYLHGKSLF PEKRNFKELT MRKRSIVTPE 360
  361 DSEEVYPYIS EFVAASNVSE EKGPKSFANL AFITIFSHFF YHIDDMWRST LGLFSLIPQI 420
  421 IGIIYLTVMF TGRELDTFMQ FGGQVVNEFI NYVVKVSLKY PRPADIEYGV GYGMPSSHSQ 480
  481 FMGFFSAYMI AWDYKYRRSQ CFSMLSFAKY AIYLTLSTFV CSSRYLLDFH YLTQVVYGYM 540
  541 IGFGVGLFWV YLVGKLRSLG VTKWLLSLPP LQFFYIKDTI PHSKDNHKRQ WLESKQFKNQ 600
  601 KSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..361] PSI-BLAST 78.69897 Palmitoyl protein thioesterase 1
    2 View Details [362..603] PSI-BLAST 8.221849 No description for 2akcA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • palmitoyl-(protein) hydrolase activity
    		•  7.84854320744165 bayes_pls_golite062009
  • hydrolase activity
    		•  4.09944423676394 bayes_pls_golite062009
  • peptidase activity
    		•  2.579037452232 bayes_pls_golite062009
  • acetylcholinesterase activity
    		•  2.37279517515601 bayes_pls_golite062009
  • palmitoyl-CoA hydrolase activity
    		•  2.35941833736344 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.29616929491964 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.11440496336538 bayes_pls_golite062009
  • carboxylesterase activity
    		•  2.10340684157921 bayes_pls_golite062009
  • lipase activity
    		•  1.95656432876646 bayes_pls_golite062009
  • serine hydrolase activity
    		•  1.74304544475032 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  1.55367000864476 bayes_pls_golite062009
  • catalytic activity
    		•  1.39629727416851 bayes_pls_golite062009
  • acyl-CoA thioesterase activity
    		•  1.04921581031052 bayes_pls_golite062009
  • binding
    		•  0.978846093152455 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.90303666778029 bayes_pls_golite062009
  • protein binding
    		•  0.890384359682543 bayes_pls_golite062009
  • receptor binding
    		•  0.845720597560984 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.73146656929653 bayes_pls_golite062009
  • dolichyldiphosphatase activity
    		•  0.632928131165061 bayes_pls_golite062009
  • cholinesterase activity
    		•  0.4381742778062 bayes_pls_golite062009
  • acylglycerol lipase activity
    		•  0.345658974420231 bayes_pls_golite062009
  • heparin binding
    		•  0.140386417117496 bayes_pls_golite062009
  • phospholipase activity
    		•  0.1336535306364 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  0.120715665971321 bayes_pls_golite062009
  • triglyceride lipase activity
    		•  0.05324087110088 bayes_pls_golite062009
  • juvenile hormone epoxide hydrolase activity
    		•  0.0481017624758091 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.00117419779800387 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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