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Protein Overview: SPCC18B5.08c

General Information:
Name(s) found: SPCC18B5.08c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • isoleucine-tRNA ligase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 973 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: isoleucyl-tRNA aminoacylation [ISSLink to PubMed article]
    mitochondrial translation [RCALink to PubMed article]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    zinc ion binding [IEA]
    isoleucine-tRNA ligase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSYISSLP KGHNHICCKQ AGRFLSSQAD LKKYSESLCL PKTSFPIKPN VKGNNEKYFK  60
   61 SITSDLYEWQ KENLNKEDSF VLLDGPPFAN GRLHIGHALN KILKDIINRW QLLKGRSVHY 120
  121 VPGWDCHGLP IESKAIKANA ERKSSLEIRK IAKDFANSAV QEQLMMFQRM AVMGDWPSRY 180
  181 ITMSDKFEIA ELKVFLSLLQ KDLIFRQNKP VYWSSSSRSA LAESEIEYDD NHVSTSIYFT 240
  241 FPVNSFSIDG CEYNNVKALV WTTTPWTIPS NLALSYHPEI NYGLYQHNNS IYLMSDNLVP 300
  301 NLDFMQGAKR LASCPSDIIS SFTYENPLLP KQSFPFLQSN YVTNDIGTGI VHVAPGHGME 360
  361 DYLLGLENNL RPFSPLDDYG RYTKEALDGS LEGLEVLGDG GKKVISIMKN QNMIVKVSPY 420
  421 KHRYPYDWRT HKPLILRATP QWFISLENER KTAIKALDSV KMIPPNSRAR LLGFLNGRPE 480
  481 WCISRQRAWG LPIPVLYEKG TKIPLLTVKS VSYIIEKMEV EGVDSWFNDT ENNGHAQWVH 540
  541 PDYRNKEYIR GTETLDVWFD SGTSWTTIAP RKNKPLIDLC LEGSDQHRGW FQSLLLTYTA 600
  601 YQSKPEAPFS TLFTHGFIFD ERGQKQSKSL GNVTDPEDVI NGKLLKGKKL PYGVDLLRLW 660
  661 VASCDSTNDT NLGPNILTQV GESLKKWRLT SRFCLGNLHD WNTSSSVDVG ELRGIDKLAL 720
  721 VQLDKFQTEI RELYESYSIN KVVHHLNYFM NSFLSSTYFD AVKDRLYADL PNSVSRRSVQ 780
  781 TVLYHSLLTL IWAISPITPL LAQEIWQSLP DSYLNSSYQT PFHAGETHLI SSLRSKVDLL 840
  841 DRKFLIKEYL VLQQLKYSIN LLITAARENL TIKNSLEAYV VIKSKSQSLL SFLKNYSSDL 900
  901 PFLFNTSKVF INEIPENLKL ASVTQPEVQL DYGVANISLF FSNQQKCLRC WMHTAHEDGL 960
  961 CDRCESVLAQ LKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..973] PSI-BLAST 1000.0 Isoleucyl-tRNA synthetase (IleRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • valine-tRNA ligase activity
    		•  7.13767629265822 bayes_pls_golite062009
  • isoleucine-tRNA ligase activity
    		•  6.38633897147986 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • leucine-tRNA ligase activity
    		•  2.62601062778624 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.56893064485672 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • binding
    		•  0.485102284225571 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.449504767632354 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle