YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: pub2

General Information:
Name(s) found: pub2 / SPAC1805.15c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • ubiquitin-protein ligase Pub2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 671 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    cell cortex of cell tip [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    extrinsic to membrane [IEA]
    Biological Process: protein ubiquitination [RCALink to PubMed article]
    Molecular Function: ubiquitin-protein ligase activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENIRFEVQL TILHVEGLWK NGLLRSLKPY LLISVDDDQF IKTNVASGTL RLSWGFTQKL  60
   61 TVSPQSIILL QLFDEKQKNE TSDGFVGLGA AVVNSFLPFN NPKDDYKTRI TLRSPSGSYR 120
  121 GSVVCLFKRS KFLPEELPAD KSQICTDIID DASGCAWETR IDEFGHVYYL KSPQLSVISA 180
  181 ISHEKLENLT PKQLKEVFSQ FLFNNQSKSS LKINLEYKVI KHLLEHYPLA LSVRQQVAVE 240
  241 KGPLPAGWEM RLSEDYHVYF VDHSTKTTTW SDPRDNVVAS DSVSENTDSI QQINDEYQRK 300
  301 IAYMYDRPEM AVNDAQLQLK VSRATTFEDA YDIISKLSVS DMKKKLLIRF RNEDGLDYGG 360
  361 VSREFFYILS HAIFNPGYSL FEYATDDNYG LQISPLSSVN PDFRSYFRFV GRVMGLAIYH 420
  421 RRYLDVQFVL PFYKRILQKP LCLEDVKDVD EVYYESLKWI KNNDVDESLC LNFSVEENRF 480
  481 GESVTVDLIP NGRNIAVNNQ NKMNYLKALT EHKLVTSTEE QFNALKGGLN ELIPDSVLQI 540
  541 FNENELDTLL NGKRDIDVQD WKRFTDYRSY TETDDIVIWF WELLSEWSPE KKAKLLQFAT 600
  601 GTSRLPLSGF KDMHGSDGPR KFTIEKVGHI SQLPKAHTCF NRLDIPPYNS KEELEQKLTI 660
  661 AIQETAGFGT E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 22.69897 Synaptogamin I
    2 View Details [206..275] FFAS03 2.87 Splicing factor prp40
    3 View Details [276..671] PSI-BLAST 135.0 Conformational Flexibility Underlies Ubiquitin Ligation Mediated by the WWP1 HECT domain E3 Ligase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • proline-rich region binding
    		•  3.98603472468613 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  2.50663692075518 bayes_pls_golite062009
  • binding
    		•  2.36222118356464 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  2.33627990300135 bayes_pls_golite062009
  • transcription factor binding
    		•  1.73081671364316 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.67021314973391 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.64250861692227 bayes_pls_golite062009
  • protein binding
    		•  1.27041711914941 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.23640210204205 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  0.9455445085372 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  0.863094487787088 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  0.863094487787088 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  0.863094487787088 bayes_pls_golite062009
  • transcription activator activity
    		•  0.836627609051151 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.70472974102432 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.572760201007946 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.539489048525578 bayes_pls_golite062009
  • transferase activity
    		•  0.385387347513497 bayes_pls_golite062009
  • catalytic activity
    		•  0.231344568578849 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.179456065780754 bayes_pls_golite062009
    3
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  7.14616396317218 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  6.99796579811325 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.03005793772151 bayes_pls_golite062009
  • proline-rich region binding
    		•  4.88459817006763 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.50502148129705 bayes_pls_golite062009
  • sodium channel inhibitor activity
    		•  3.64966529121446 bayes_pls_golite062009
  • phosphothreonine binding
    		•  2.95470890163581 bayes_pls_golite062009
  • phosphoserine binding
    		•  2.95470890163581 bayes_pls_golite062009
  • binding
    		•  2.32045312021486 bayes_pls_golite062009
  • ion channel inhibitor activity
    		•  2.14402963004533 bayes_pls_golite062009
  • channel inhibitor activity
    		•  2.14402963004533 bayes_pls_golite062009
  • ligase activity
    		•  2.05648169328967 bayes_pls_golite062009
  • RNA polymerase binding
    		•  1.8762146737407 bayes_pls_golite062009
  • protein binding
    		•  1.29390544644063 bayes_pls_golite062009
  • sodium channel regulator activity
    		•  1.19047973745862 bayes_pls_golite062009
  • catalytic activity
    		•  1.15152367676155 bayes_pls_golite062009
  • ubiquitin-ubiquitin ligase activity
    		•  0.598436219078807 bayes_pls_golite062009
  • transcription factor binding
    		•  0.585725073778084 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.509776214744915 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.376852535152545 bayes_pls_golite062009
  • DNA binding
    		•  0.187697131456126 bayes_pls_golite062009
  • channel regulator activity
    		•  0.072778668515899 bayes_pls_golite062009
    		• 0.051942165438844 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle