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Protein Overview: mbx2

General Information:
Name(s) found: mbx2 / SPBC317.01 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • MADS-box transcription factor Pvg4 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 372 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: fungal-type cell wall biogenesis [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEA]
    4,6-pyruvylated galactose residue biosynthetic process [IMPLink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    Molecular Function: transcription factor activity [IEA]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]
    sequence-specific DNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRKKISIAP ITDDRSRSVT FVKRKQGLYK KAYELAVLAD CEVAVTVIDR KGRLHVFCSS  60
   61 DYQRTLQQLN TLSIYELKNR SHFSSSPVEE SSTVSPETTT GSFTPLNNKH LKSQDQPLSD 120
  121 SQLDTGDSPA TSETTVQDYN PQVQSYCRPE PLSSNHVRSC PPFPPTQHHH PHTRPPHHPP 180
  181 HPHFHNNNYP PPYCFQSPVS PGATVPLQHH SPYPSDNGFP GHRRQTHFAP YYYPQRATSP 240
  241 SLKQVPTYLG THVLQQDQST YDQKVLMPPA SYLSSPNQYT LKNVSPGNPA CPPFLYEHPN 300
  301 PQLTPEMFDV KQGSPIPPTA YSGSSCETSQ HTIANTPFLA YDRSPSLTNQ EAESSFQDVA 360
  361 SISPHSLSDV KY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] PSI-BLAST 29.221849 Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2
    2 View Details [86..199] deduced N/A No confident structure predictions are available.
    3 View Details [200..372] MSA 29.372997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleic acid binding
    		•  3.20423226810641 bayes_pls_golite062009
  • DNA binding
    		•  3.19357863925229 bayes_pls_golite062009
  • binding
    		•  3.13725722282473 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.13318816174147 bayes_pls_golite062009
  • transcription factor activity
    		•  2.59884999361198 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.01575603719104 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.0615361674883 bayes_pls_golite062009
  • protein binding
    		•  1.0452482001033 bayes_pls_golite062009
  • transcription activator activity
    		•  0.69462470268703 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle