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Protein Overview: SPAC19B12.08

General Information:
Name(s) found: SPAC19B12.08 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • peptidase family C54 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 320 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: protein delipidation [ISSLink to PubMed article]
    autophagic vacuole assembly [ISSLink to PubMed article]
    autophagy [IMPLink to PubMed article]
    protein maturation by peptide bond cleavage [ISS]
    protein targeting to vacuole [ISSLink to PubMed article]
    macroautophagy [IC]
    cellular response to nitrogen starvation [IMPLink to PubMed article]
    Molecular Function: cysteine-type endopeptidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELMARFLER YLHFAPTNTE PPGTLIWFLG HSYKIEDSQW PEKFLYDSFS LITITYRSGI  60
   61 EGLENMTSDT GWGCMIRSTQ TLLANCLRIC YPEKQLKEIL ALFADEPSAP FSIHQFVTMG 120
  121 KTLCDINPGQ WFGPTTSCSC VARLSDQNPD VPLHVYVARN GNAIYRDQLS KVSFPVLLLI 180
  181 PTRLGIDSIN ESYYDQLLQV FEIRSFVGIT GGRPRSAHYF YARQNQYFFY LDPHCTHFAH 240
  241 TTTQPASEET FHSATLRRVA IQDLDPCMIF GFLIRDEEEW HSFEANQKYF ADIVQIFDSE 300
  301 PQPVETHDDF VLDENVEDHL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..320] PSI-BLAST 128.0 Structure of human Atg4b

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cysteine-type peptidase activity
    		•  3.05412701733177 bayes_pls_golite062009
  • peptidase activity
    		•  2.8192612691912 bayes_pls_golite062009
  • hydrolase activity
    		•  2.66167923792227 bayes_pls_golite062009
  • endopeptidase activity
    		•  2.56654871607946 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.55227247835105 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  2.06332547782769 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.95802900199539 bayes_pls_golite062009
  • microtubule binding
    		•  1.80986894246631 bayes_pls_golite062009
  • tubulin binding
    		•  1.65326788939069 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.61845762872724 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.43988355875744 bayes_pls_golite062009
  • binding
    		•  1.3276268995308 bayes_pls_golite062009
  • protein binding
    		•  1.27241282337344 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.913227912866975 bayes_pls_golite062009
  • transporter activity
    		•  0.69523261160023 bayes_pls_golite062009
  • DNA binding
    		•  0.683141655614916 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.667279936700542 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.467924587720185 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.439003000540428 bayes_pls_golite062009
  • structural molecule activity
    		•  0.297752217869698 bayes_pls_golite062009
  • calcium-dependent cysteine-type endopeptidase activity
    		•  0.196538841514154 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.125654358663332 bayes_pls_golite062009
  • transferase activity
    		•  0.0852393573521809 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0241561776323942 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0199148741009585 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle