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Protein Overview: rgf1

General Information:
Name(s) found: rgf1 / SPCC645.07 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • RhoGEF for Rho1, Rgf1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1334 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cell septum [IDALink to PubMed article]
    cell tip [IDALink to PubMed article]
    barrier septum [IDALink to PubMed article]
    cell cortex of cell tip [IDALink to PubMed article]
    Biological Process: regulation of cell shape [IGILink to PubMed article]
    fungal-type cell wall biogenesis [IGILink to PubMed articleLink to PubMed article][IMPLink to PubMed article]
    positive regulation of Rho protein signal transduction [IGILink to PubMed article]
    regulation of small GTPase mediated signal transduction [IGILink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    positive regulation of bipolar cell growth [IMPLink to PubMed article]
    regulation of 1,3-beta-glucan biosynthetic process [IGILink to PubMed article][IMPLink to PubMed article]
    actin cortical patch localization [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    Rho guanyl-nucleotide exchange factor activity [IGILink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYRHPNALG VNESSRAYEE IFGAPRKREP ARTVSTPAFM EPAPVSKKPL PPPTRRLPRK  60
   61 PLPFRSTSLQ PPSSQPPAPP THQREASPVK NIEHSESFPS VFGTSNNHQI VPLTLKDGND 120
  121 FGALYASLNT TPHFPQVSNH APNNSNSPSL TWHTSSGDDS NQNPFFVRRQ SQSSTSPVSD 180
  181 SVDENLLSAV SSVTESVETN LHLDQNYPYG SPVRSSKNPF LSSNSRLPTD DSSHTVGSHS 240
  241 FTSGTHPPIV SSNSAFTLPN AVTPAAQAPL IRSVSEYPAN VSPPAQSLQL PKSTSNPADL 300
  301 HLSIASASSH KNIFSGLDVF SNVFHGPSTT LRDREHDMRN RSFDHSTLAH YEAVKQQRLG 360
  361 VEPTARSFTL SSYKSRASGN SLINDRSSTT TPTFVNSEAS SPVHKNKRRR RIYAALLSRV 420
  421 ASELLDRLQL GDITKDGLIY SNAFTGDHAV TVLMGIIHTS DRNLALLVGR SLDAQKFIHD 480
  481 VTYDHRLRDS HREIYQLQGT GYRPFLRAND NASINNKNHH KELEDNESGT RISPSTLGDT 540
  541 SFPNGIFTLL THCYSPTCAK DHPCYSISCP RRLEQQHRLF AKMRANTEQS SSLAFDDKEQ 600
  601 KLWIHSVPQE IAYSVSDRER KRQEVICEVI YTERDFVKDL EYLRDYWIKP LWASSCIPER 660
  661 KKEKFIRTVF LNALEVQAVN SKLAEALTKR QNYKPIVDNI ADIFLEHVPK FEPFIRYGAG 720
  721 QLYGKYEFEK EKSSNPAFAK FVSDVERLKE SRKLELNGYL TKPTTRLARY PLLLEAVLKY 780
  781 TDEGNPDKQD IPKVINIVRG FLSRLNVESG KAENKFNLFH LNQQLVFKPG EHYDLHLLDA 840
  841 NRQLIFKGPL KKRSAGSTSS ESASDVTLFL FDHALLIVKP KTINKRELLK VFQRPIPLLL 900
  901 LQLFLVDDNG LRIPYSSKQQ LAAVSKAANG KPPSRFYPFS LQLLGRRGYE ITLYATTEVS 960
  961 RDKWLEHIDN QQTLLQHRNQ WFESVTICSN FFVGDNKVNA IGVYDSGRRL LYGTDTGVYV1020
 1021 SLRKANSPLQ FKPVRALNIP NISQLEVIEE YSLLLLLSDK VLYSYPLEMI DADTTQAPKK1080
 1081 ARKVSGHTTF FRVGICLGKV LVCAVKSSVL SATIKVFEPV TNYSKTRNMP SLKKFLTVNQ1140
 1141 DPLRIVKELY IPTESTSVHF LKNKLCVGCT RGFEVVSLDN LETQSLLDPA DTSLEFVEKK1200
 1201 ENVKPIAIYR MNGGEFLLCY SQFAFYVNRD GWRSRPTWFV VWEGSPQNFA LSYPYILAFE1260
 1261 PTFIEIRHVE TSELIHVISG RNIRLLADGR GKLGDGGEIF YACDQRGENC ETSVVCSLRL1320
 1321 TSAAAHAKEQ HVDK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..404] PSI-BLAST 4.154902 No description for 1y0fB was found.
    2 View Details [405..528] FFAS03 4.16 Segment polarity protein Dishevelled-1
    3 View Details [529..604] deduced N/A No confident structure predictions are available.
    4 View Details [605..993] PSI-BLAST 84.69897 No description for 2pz1A was found.
    5 View Details [994..1170] deduced N/A No confident structure predictions are available.
    6 View Details [1171..1334] MSA 2.064971 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.83417082121324 bayes_pls_golite062009
  • DNA binding
    		•  4.45307043231712 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.32650610181001 bayes_pls_golite062009
  • transcription factor activity
    		•  3.74401182888821 bayes_pls_golite062009
  • binding
    		•  3.37660003833383 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.13497236448364 bayes_pls_golite062009
  • transcription activator activity
    		•  2.00002087172734 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.87251560747782 bayes_pls_golite062009
  • protein binding
    		•  1.77689943618029 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.22243136502304 bayes_pls_golite062009
  • transcription factor binding
    		•  0.674981262070685 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle