YRC Public Data Repository - Protein Structure Prediction

Protein:	rgf1
Organism:	Schizosaccharomyces pombe
Length:	1334 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rgf1.

Description	E-value	Query Range	Subject Range
gi\|32408735, gi\|... - gi\|32408735\|ref\|XP_324848.1\| hypothetical protein [Neurospora crassa], gi\|28927621\|gb\|EAA36572.1\| hy... gi\|85074881 - gi\|85074881\|ref\|XP_965808.1\| hypothetical protein NCU00668.1 [Neurospora crassa OR74A]	802.0	[0..75]	[1314..6]
gi\|46128389, gi\|... - gi\|46128389\|ref\|XP_388748.1\| hypothetical protein FG08572.1 [Gibberella zeae PH-1], gi\|42548590\|gb\|E...	783.0	[0..74]	[1314..8]
gi\|39971195, gi\|... - gi\|39971195\|ref\|XP_366988.1\| hypothetical protein MG03064.4 [Magnaporthe grisea 70-15], gb\|EAA47821....	781.0	[0..20]	[1314..3]
gi\|114191837, gi... - gi\|115398730\|ref\|XP_001214954.1\| hypothetical protein ATEG_05776 [Aspergillus terreus NIH2624], gi\|1...	770.0	[0..108]	[1314..8]
gi\|45199103, gi\|... - gi\|45199103\|ref\|NP_986132.1\| AFR585Wp [Ashbya gossypii ATCC 10895], gi\|44985178\|gb\|AAS53956.1\| AFR58... gi\|44985178 - gi\|44985178\|gb\|AAS53956.1\| AFR585Wp [Ashbya gossypii ATCC 10895]	765.0	[0..184]	[1314..102]
gi\|67537098, gi\|... - gi\|67537098\|ref\|XP_662323.1\| hypothetical protein AN4719.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	761.0	[0..117]	[1314..13]
gi\|50303861, gi\|... - gi\|50303861\|ref\|XP_451877.1\| unnamed protein product [Kluyveromyces lactis], gi\|49641009\|emb\|CAH0227... gi\|16611806, gi\|... - gi\|49641009\|emb\|CAH02270.1\| KLLA0B07799p [Kluyveromyces lactis], gi\|16611806\|gb\|AAL27369.1\|AF421953_...	760.0	[0..105]	[1314..28]
gi\|70998102, gi\|... - gi\|70998102\|ref\|XP_753782.1\| Rho guanyl nucleotide exchange factor (Rom2) [Aspergillus fumigatus Af2...	759.0	[0..130]	[1314..19]
gi\|88182284, gi\|... - gi\|88182284\|gb\|EAQ89752.1\| conserved hypothetical protein [Chaetomium globosum CBS 148.51], gi\|11619...	753.0	[0..60]	[1314..42]
gi\|169778969 - gi\|169778969\|ref\|XP_001823949.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83772688 - gi\|83772688\|dbj\|BAE62816.1\| unnamed protein product [Aspergillus oryzae]	748.0	[0..124]	[1314..33]

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Predicted Domain #1

Region A:
Residues: [1-404]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYRHPNALG VNESSRAYEE IFGAPRKREP ARTVSTPAFM EPAPVSKKPL PPPTRRLPRK  60
   61 PLPFRSTSLQ PPSSQPPAPP THQREASPVK NIEHSESFPS VFGTSNNHQI VPLTLKDGND 120
  121 FGALYASLNT TPHFPQVSNH APNNSNSPSL TWHTSSGDDS NQNPFFVRRQ SQSSTSPVSD 180
  181 SVDENLLSAV SSVTESVETN LHLDQNYPYG SPVRSSKNPF LSSNSRLPTD DSSHTVGSHS 240
  241 FTSGTHPPIV SSNSAFTLPN AVTPAAQAPL IRSVSEYPAN VSPPAQSLQL PKSTSNPADL 300
  301 HLSIASASSH KNIFSGLDVF SNVFHGPSTT LRDREHDMRN RSFDHSTLAH YEAVKQQRLG 360
  361 VEPTARSFTL SSYKSRASGN SLINDRSSTT TPTFVNSEAS SPVH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.154902
Match:	1y0fB
Description:	No description for 1y0fB was found.

Predicted Domain #2

Region A:
Residues: [405-528]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNKRRRRIYA ALLSRVASEL LDRLQLGDIT KDGLIYSNAF TGDHAVTVLM GIIHTSDRNL  60
   61 ALLVGRSLDA QKFIHDVTYD HRLRDSHREI YQLQGTGYRP FLRANDNASI NNKNHHKELE 120
  121 DNES

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.16
Match:	1fshA
Description:	Segment polarity protein Dishevelled-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.83417082121324	bayes_pls_golite062009
DNA binding	4.45307043231712	bayes_pls_golite062009
nucleic acid binding	4.32650610181001	bayes_pls_golite062009
transcription factor activity	3.74401182888821	bayes_pls_golite062009
binding	3.37660003833383	bayes_pls_golite062009
sequence-specific DNA binding	2.13497236448364	bayes_pls_golite062009
transcription activator activity	2.00002087172734	bayes_pls_golite062009
transcription repressor activity	1.87251560747782	bayes_pls_golite062009
protein binding	1.77689943618029	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.22243136502304	bayes_pls_golite062009
transcription factor binding	0.674981262070685	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [529-604]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTRISPSTLG DTSFPNGIFT LLTHCYSPTC AKDHPCYSIS CPRRLEQQHR LFAKMRANTE  60
   61 QSSSLAFDDK EQKLWI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [605-993]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSVPQEIAYS VSDRERKRQE VICEVIYTER DFVKDLEYLR DYWIKPLWAS SCIPERKKEK  60
   61 FIRTVFLNAL EVQAVNSKLA EALTKRQNYK PIVDNIADIF LEHVPKFEPF IRYGAGQLYG 120
  121 KYEFEKEKSS NPAFAKFVSD VERLKESRKL ELNGYLTKPT TRLARYPLLL EAVLKYTDEG 180
  181 NPDKQDIPKV INIVRGFLSR LNVESGKAEN KFNLFHLNQQ LVFKPGEHYD LHLLDANRQL 240
  241 IFKGPLKKRS AGSTSSESAS DVTLFLFDHA LLIVKPKTIN KRELLKVFQR PIPLLLLQLF 300
  301 LVDDNGLRIP YSSKQQLAAV SKAANGKPPS RFYPFSLQLL GRRGYEITLY ATTEVSRDKW 360
  361 LEHIDNQQTL LQHRNQWFES VTICSNFFV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.69897
Match:	2pz1A
Description:	No description for 2pz1A was found.

Predicted Domain #5

Region A:
Residues: [994-1170]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDNKVNAIGV YDSGRRLLYG TDTGVYVSLR KANSPLQFKP VRALNIPNIS QLEVIEEYSL  60
   61 LLLLSDKVLY SYPLEMIDAD TTQAPKKARK VSGHTTFFRV GICLGKVLVC AVKSSVLSAT 120
  121 IKVFEPVTNY SKTRNMPSLK KFLTVNQDPL RIVKELYIPT ESTSVHFLKN KLCVGCT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [1171-1334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGFEVVSLDN LETQSLLDPA DTSLEFVEKK ENVKPIAIYR MNGGEFLLCY SQFAFYVNRD  60
   61 GWRSRPTWFV VWEGSPQNFA LSYPYILAFE PTFIEIRHVE TSELIHVISG RNIRLLADGR 120
  121 GKLGDGGEIF YACDQRGENC ETSVVCSLRL TSAAAHAKEQ HVDK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: