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Protein Overview: SPAC1B3.08

General Information:
Name(s) found: SPAC1B3.08 [Sanger Pombe]
Description(s) found:
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  • pir||T38026 hypothetical protein SPAC1B3.08 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|3183362|sp|O13873.1|CSN12_SCHPO RecName: Full=Protein CSN12 homolog [NCBI NR]
  • gi|2330742|emb|CAB11237.1| COP9 signalosome complex subunit 12 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19115704|ref|NP_594792.1| COP9 signalosome complex subunit 12 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • COP9 signalosome complex subunit 12 [Sanger Pombe]
  • (O13873) Hypothetical protein C1B3.08 in chromosome I [Swiss-Prot]
  • Protein CSN12 homolog OS=Schizosaccharomyces pombe GN=csn12 PE=2 SV=1 [Swiss-Prot]
  • HYPOTHETICAL PROTEIN; SIMILAR TO S. CEREVISIAE YOL072W: O13873; [pompepVF.fasta]
  • Hypothetical protein C1B3.08 in chromosome I [pompep4896]
  • |||PINT/PCI domain (inferred from context) [pompepnew.fasta]
  • |||PINT/PCI domain (inferred from context)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|2330742|emb|CAB11237.1| SPAC1B3.08 [Schizosaccharomyces pombe]gi|3183362|sp|O13873|YE18_SCHPO Hypothetical protein C1B3.08 in chromosome Igi|7490911|pir||T38026 hypothetical protein SPAC1B3.08 - fissio [nrdb_11152004_Chlamydomonas]
  • |||PINT/PCI domain |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • |||COP9 signalosome complex subunit 12 |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • SPAC1B3.08 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC1B3.08 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Protein CSN12 homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=csn12 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 423 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: protein deneddylation [ICLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERPLPLNV YFSTINSAVA RSNSVLLAKN LSIPWGKTLT SVLNFDIPGT YSSDDVLKLT  60
   61 VERSISKNWT DIVLLHLQVL LYLVRDHDPA AAFKQQTELA QHLYREFSSG RCTGVHLPVL 120
  121 FIVCKDLRFL AINAHNAMLR RKQQLKVISV DESEENEQLE ATARLINRAF TICINDRAPL 180
  181 STSRKWGAYY IMGLLFKLYL RLDCVHLTNN VLRAMKVVEL PDISLFPKSH VVIFHYYLGI 240
  241 VAFLNQNYKN ASAELEIAFS LCHKGYNRNL ELILSYWIPT RILVNHQLPT KNLLSKFPNL 300
  301 ASVYIPLTRA LKSGNLGEFG KCLQKNETLL AKTKIYLTLE GTRDLCIRNL FRKTWIICGK 360
  361 STRLPVSVFQ IALQVAGTDL PKLHVEAILA NMISKGYMRG YISRNFETVV LSAKDPFPKN 420
  421 VST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..350] FFAS03 1.13 Vesicular transport protein sec17
    2 View Details [351..423] PSI-BLAST 5.522879 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.0556615145105 bayes_pls_golite062009
  • protein binding
    		•  1.6502679626605 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.37433494532207 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.16698845971978 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.782086955538979 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.437277381081288 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.198767743012145 bayes_pls_golite062009
  • DNA binding
    		•  0.186035324819401 bayes_pls_golite062009
  • transferase activity
    		•  0.157308242400253 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  3.38230388954255 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.38144578566524 bayes_pls_golite062009
  • DNA binding
    		•  3.30822066787723 bayes_pls_golite062009
  • binding
    		•  2.93590311675477 bayes_pls_golite062009
  • transcription factor activity
    		•  2.53517246325934 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.28622713424902 bayes_pls_golite062009
  • transcription activator activity
    		•  1.08566311616647 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.04514547811581 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.95491822926452 bayes_pls_golite062009
  • protein binding
    		•  0.890737236042485 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.804680913729793 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.59179664022664 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.42135864069093 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.249771970501337 bayes_pls_golite062009
  • transferase activity
    		•  0.064832527337659 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle