Protein Overview: SPAC1B3.08

General Information:
Name(s) found:	SPAC1B3.08 [Sanger Pombe]
Description(s) found: Found 17 descriptions. SHOW ALL	COP9 signalosome complex subunit 12 [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	423 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytosol [IDA]
Biological Process:	protein deneddylation [IC]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERPLPLNV YFSTINSAVA RSNSVLLAKN LSIPWGKTLT SVLNFDIPGT YSSDDVLKLT  60
   61 VERSISKNWT DIVLLHLQVL LYLVRDHDPA AAFKQQTELA QHLYREFSSG RCTGVHLPVL 120
  121 FIVCKDLRFL AINAHNAMLR RKQQLKVISV DESEENEQLE ATARLINRAF TICINDRAPL 180
  181 STSRKWGAYY IMGLLFKLYL RLDCVHLTNN VLRAMKVVEL PDISLFPKSH VVIFHYYLGI 240
  241 VAFLNQNYKN ASAELEIAFS LCHKGYNRNL ELILSYWIPT RILVNHQLPT KNLLSKFPNL 300
  301 ASVYIPLTRA LKSGNLGEFG KCLQKNETLL AKTKIYLTLE GTRDLCIRNL FRKTWIICGK 360
  361 STRLPVSVFQ IALQVAGTDL PKLHVEAILA NMISKGYMRG YISRNFETVV LSAKDPFPKN 420
  421 VST

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..350]	FFAS03	1.13	Vesicular transport protein sec17
2	View Details	[351..423]	PSI-BLAST	5.522879	Solution structure of the PCI domain

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
binding	2.0556615145105	bayes_pls_golite062009
protein binding	1.6502679626605	bayes_pls_golite062009
small conjugating protein ligase activity	1.37433494532207	bayes_pls_golite062009
ubiquitin-protein ligase activity	1.16698845971978	bayes_pls_golite062009
acid-amino acid ligase activity	0.782086955538979	bayes_pls_golite062009
nucleic acid binding	0.437277381081288	bayes_pls_golite062009
transcription regulator activity	0.198767743012145	bayes_pls_golite062009
DNA binding	0.186035324819401	bayes_pls_golite062009
transferase activity	0.157308242400253	bayes_pls_golite062009

2

Term	Confidence	Notes
transcription regulator activity	3.38230388954255	bayes_pls_golite062009
nucleic acid binding	3.38144578566524	bayes_pls_golite062009
DNA binding	3.30822066787723	bayes_pls_golite062009
binding	2.93590311675477	bayes_pls_golite062009
transcription factor activity	2.53517246325934	bayes_pls_golite062009
sequence-specific DNA binding	1.28622713424902	bayes_pls_golite062009
transcription activator activity	1.08566311616647	bayes_pls_golite062009
small conjugating protein ligase activity	1.04514547811581	bayes_pls_golite062009
transcription repressor activity	0.95491822926452	bayes_pls_golite062009
protein binding	0.890737236042485	bayes_pls_golite062009
ubiquitin-protein ligase activity	0.804680913729793	bayes_pls_golite062009
acid-amino acid ligase activity	0.59179664022664	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.42135864069093	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.249771970501337	bayes_pls_golite062009
transferase activity	0.064832527337659	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.88

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle