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Protein Overview: SPBC3D6.13c

General Information:
Name(s) found: SPBC3D6.13c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • protein disulfide isomerase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 726 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum membrane [ISSLink to PubMed article]
    integral to membrane [IEA]
    Golgi apparatus [IDALink to PubMed article]
    Biological Process: cell redox homeostasis [IEA]
    ER-associated protein catabolic process [ISS]
    protein retention in ER lumen [ISSLink to PubMed article]
    Molecular Function: protein disulfide isomerase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSNTFGSVM RISWVVAFIT MVQTLVSGVP LTDNDLESEV SKGTWFIKYY LPSCGACKRL  60
   61 GPMWDNMVEK AKEQVEGSNF HFGEVDCSKE LSSCANIRAV PTLYLYQNGE IVEEVPFGAS 120
  121 TSEASLLDFV ETHLNPDTDP DIPSDEDVLT DEDTEEVASI QPALSTSVSS LSLASTAMSK 180
  181 SASASEFSGS SVTKASKKLT SSPTSVASKK ATLSSVSKVA STSSLPVTSV SASVDPKSAA 240
  241 SKVQDAEFSI QTAPSFPKEK EEKENTEETE ESKKSINPTG TSKALALDAD IDAALTDKEG 300
  301 WFIQFYSSEC DDCDDVSTAW YAMANRMRGK LNVAHINCAV SKRACKQYSI QYFPTFLFFK 360
  361 EEAFVEYVGL PNEGDLVSFA EEAANFEIRE VELLDTVNAE KNGDVFFLYF YDDDSAEYLN 420
  421 IIRKTGIQLL GHANLYLTTS QQIAKKYRVV SFPKLIVVRD GIASYYPAKM AQDNKDYRRI 480
  481 LGWMKNNWLP VLPELRTSNS KEIFNDESVV LFLLNPELDD FDETKRTAQK IATEFLDEEG 540
  541 RTYQSNWQKE TDKKNSLVNE AEEKNDLEAI EAAKNFHVNG KPSPTRFAWV NGKFWAQWLR 600
  601 KFDIDIEATG PRVIVYNAAQ DIYWDETAKG TPISIEKDTV FDIIKQVETD PDHLKFKILK 660
  661 KNLGVEYLES YGLNIRVLYM VLGIVTVGIL VWYFSGRRAR TLQRRRHSTP ILPVSMRSTG 720
  721 NSGKFD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..143] PSI-BLAST 32.0 HUMAN PROTEIN DISULFIDE ISOMERASE, NMR, 40 STRUCTURES
    2 View Details [144..263] deduced N/A No confident structure predictions are available.
    3 View Details [264..726] PSI-BLAST 80.0 Crystal Structure of Yeast Protein Disulfide Isomerase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein disulfide isomerase activity
    		•  2.05206748531532 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  2.05206748531532 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  1.83987272812734 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  1.5535855642475 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • binding
    		•  0.630214408223227 bayes_pls_golite062009
  • hydrolase activity
    		•  0.343949262540688 bayes_pls_golite062009
  • protein binding
    		•  0.034515546627104 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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