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Protein Overview: kap111

General Information:
Name(s) found: kap111 / SPAC22G7.02 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • karyopherin Kap111 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 990 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nucleus [IDALink to PubMed article]
    nuclear membrane [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    nuclear pore [TASLink to PubMed article]
    Biological Process: nucleocytoplasmic transport [TASLink to PubMed article]
    protein targeting [RCALink to PubMed article]
    Molecular Function: GTP binding [NASLink to PubMed article]
    protein transporter activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGNEIAHAK KLVYDLYSGS LSPSAIAATE KELQKAQRSQ QGWNIGLFML QSKDVYEQFF  60
   61 GALTLQMKIN TQLETLSDKD LVQLFVQLLQ KLLWDDGLPA LVERKVICTL ASLTIKYELE 120
  121 KKEEASLKVI YCLFCNKLEF FNADMNAASV LNNLFPPASS RNAQLTASYI NELLLELSFS 180
  181 IYTKENEDAL FNNVFRPCSN IIVSVLVFIF TNYSLDLSKE KNVAALEEAL NCMIAISSYL 240
  241 AKASVSVQSV LPAFTECMDL TVNCIALDEV SEKAMNCLAD LLANYSNFIT QPTIERLWTI 300
  301 LTGPWGETHL QQELEDPDSG EENDYSFLNI VIGFAEAMLP QIIDHIQEEK SIRLLYILAS 360
  361 LLSFPGYAIV EEKVSWRTLE FWTTLIEDFS MSKAATDPSK DEIFKQIAFS VVEKAWWKML 420
  421 LPSPEQWNSW PSSSRDSFNS YRRDLGDLLE SSYSIFGERL YAMYITTIEN FFSDGTGSPQ 480
  481 SLEVSFYCLC CILEYDTNDS DTLDAWLTRL FETSFAIKAS AFQNPQLLKT CSQLLSSCSC 540
  541 FLQNHPQYLN ISLPVLFDAL HISETSIQMT VSRSIHTLCT TCASHLLTEI DGFMAVVEEL 600
  601 TPKLVYVPSV LEKIYSSVGY VTQRIEDIEL RISYLMRLLN CILAQLQPSL YPNLEIFENV 660
  661 LKSCLQSVAG VALSQSPIGE SPIIDVEQST QETTFWQQSC IAEFQAKLIS FLTHSESMAL 720
  721 QYSDVVGLIC KIMIAGLNEV EPSPFSLPIV TTIQYFCDRF TEFPAAVLLT LGSAILTCPY 780
  781 GQTDIIDKVL IDMCSSIQNS VVIINEESFM NNIDITVELY HFFSIILQKH PSFLETMYPD 840
  841 FTQLILNRAI NLLGKPERLL ESAAGQFIIS FITSEKSDLL NTHTDFVNAI RSPLIAKILL 900
  901 GFGGNASRSS LPLLSDILGK LKAQNFSATR ACLTQSLEEE GFPSRNVSNE IKRRFLTDLL 960
  961 KARIKDKVKQ FWILCKGLES TPYGNSSWTF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..901] PSI-BLAST 91.39794 Karyopherin beta2
    2 View Details [902..990] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  3.92743254165888 bayes_pls_golite062009
  • binding
    		•  2.61658111885029 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • protein binding
    		•  2.13529412360404 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.06444045538785 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  1.29390474721722 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.27627067567874 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.09652988954158 bayes_pls_golite062009
  • RNA binding
    		•  0.97764812194782 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.248585912061178 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.169755106399802 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0405268469927988 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle