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Protein Overview: vps16

General Information:
Name(s) found: vps16 / SPAC824.05 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • HOPS complex subunit Vps16 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 835 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    HOPS complex [ISSLink to PubMed article]
    Biological Process: vacuole organization [ISSLink to PubMed article]
    vesicle docking [ISSLink to PubMed article]
    late endosome to vacuole transport [ISSLink to PubMed article]
    vacuole fusion, non-autophagic [ISSLink to PubMed article]
    protein targeting to vacuole [ISSLink to PubMed article]
    Golgi to endosome transport [ISSLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPSIKYPIY EWELLQDTYY QKSAIGKAEW EYIDPVDFMF AVAPCGGAIA ITRSESNLQS  60
   61 NYKYDQVPMY SICVFCLSGQ LLQTLTWDKT SLVGMGWNEN EELIVVSKQG QVRVYNLLGE 120
  121 FHQFSLGKGV ENIGIRECQF SEGGVFALLQ NDTFISITGF EEPWRKTYAS IPFNTLEYYN 180
  181 IDSWALIPNP FSPDLGMDIV VTVGPHILQI DEQDSQLHSI SSLQHVSHIS ISPNARYLAL 240
  241 YESVGKVRVI SSDFSKELLD LRLPETVAEA SLKQMAWCGN DAVVLVHENL LTLVGPFGGS 300
  301 VPYLYNHTPI VSTEVDGVRI LTKDSSEFLR KVPAPLENIF HIGSKTPGAK LVEAFQKMKL 360
  361 KSVFAEKMLL ELKDELHDAV DTCVQASLNE FSIEWQKVLL EAASLGKNSL RMYNHQEYVD 420
  421 VCRELRVLNA ARDPNVGIYI THEEYLHLGL ERLIQRFSCR QLYGLAVQAS MWMQIPCDWV 480
  481 YIQWAQTYIK QSSEPEEVVL DNIVKRLSSR KYISYEKIAR TAYQEGRLIL STKLLDFEPL 540
  541 AKHQVMLLLN MEAYEQALKK VIETMDNNLI IYVVLQIKQQ MAIASFFQIL NEYPDAVKVY 600
  601 VEFAKKNDRK TLHDFFYQDD NKQGIAVLAV EDTLKTATVN QRITSLKSAA KVCSESKELS 660
  661 LEEKCLGDEI KLLQLQQTYE DQFTGNFVGL TVNEVVVKLI QINQTQRANK LRSDFQIPEK 720
  721 RFAWLKLRAL VAIRDWVQIE QWAGSMRRSP IGFEPFVTEI LSAGNKKEAA KYIPRCTQLT 780
  781 TQEKVDMWVQ VGDVKSASEE AAKSKSGSVL GDLLERVQTM PESRFVQNAL DQLRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..429] PSI-BLAST 35.154902 Actin interacting protein 1
    2 View Details [430..657] MSA 1.067947 View MSA. No confident structure predictions are available.
    3 View Details [658..835] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  2.43959139856243 bayes_pls_golite062009
  • binding
    		•  2.2778252170547 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.20122168933317 bayes_pls_golite062009
  • protein binding
    		•  1.24173112731149 bayes_pls_golite062009
  • transporter activity
    		•  1.21549336905926 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.734793983890004 bayes_pls_golite062009
  • actin filament binding
    		•  0.707257679204688 bayes_pls_golite062009
  • tubulin binding
    		•  0.356901755730737 bayes_pls_golite062009
  • microtubule binding
    		•  0.291759739904529 bayes_pls_golite062009
  • hydrolase activity
    		•  0.28424525033024 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle