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View Structure Prediction Details

Protein: vps16
Organism: Schizosaccharomyces pombe
Length: 835 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vps16.

Description E-value Query
Range
Subject
Range
gi|145010463, gi... - gi|39939968|ref|XP_359521.1| hypothetical protein MGG_05256 [Magnaporthe grisea 70-15], gb|EAA52564....
730.0 [0..6] [831..3]
VP16_MOUSE, VPS1... - Vacuolar protein sorting-associated protein 16 homolog OS=Mus musculus GN=Vps16 PE=1 SV=2, (Q920Q4) ...
717.0 [0..5] [815..1]
gi|88183688, gi|... - gi|88183688|gb|EAQ91156.1| hypothetical protein CHGG_03091 [Chaetomium globosum CBS 148.51], gi|1162...
713.0 [0..7] [823..5]
gi|28924513, gi|... - gi|32411285|ref|XP_326123.1| hypothetical protein [Neurospora crassa], gi|28924513|gb|EAA33636.1| hy...
gi|85109346 - gi|85109346|ref|XP_962872.1| hypothetical protein [Neurospora crassa OR74A]
698.0 [0..6] [830..4]
ENSPTRT00000024487 - null
VPS16 - vacuolar protein sorting 16 homolog (S. cerevisiae)
697.0 [0..5] [815..1]
gi|53850610, gi|... - gi|53850610|ref|NP_001005541.1| vacuolar protein sorting 16 homolog [Rattus norvegicus], gi|51980384...
694.0 [0..5] [815..1]

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Predicted Domain #1
Region A:
Residues: [1-429]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPSIKYPIY EWELLQDTYY QKSAIGKAEW EYIDPVDFMF AVAPCGGAIA ITRSESNLQS  60
   61 NYKYDQVPMY SICVFCLSGQ LLQTLTWDKT SLVGMGWNEN EELIVVSKQG QVRVYNLLGE 120
  121 FHQFSLGKGV ENIGIRECQF SEGGVFALLQ NDTFISITGF EEPWRKTYAS IPFNTLEYYN 180
  181 IDSWALIPNP FSPDLGMDIV VTVGPHILQI DEQDSQLHSI SSLQHVSHIS ISPNARYLAL 240
  241 YESVGKVRVI SSDFSKELLD LRLPETVAEA SLKQMAWCGN DAVVLVHENL LTLVGPFGGS 300
  301 VPYLYNHTPI VSTEVDGVRI LTKDSSEFLR KVPAPLENIF HIGSKTPGAK LVEAFQKMKL 360
  361 KSVFAEKMLL ELKDELHDAV DTCVQASLNE FSIEWQKVLL EAASLGKNSL RMYNHQEYVD 420
  421 VCRELRVLN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.154902
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 2.43959139856243 bayes_pls_golite062009
binding 2.2778252170547 bayes_pls_golite062009
cytoskeletal protein binding 2.20122168933317 bayes_pls_golite062009
protein binding 1.24173112731149 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
actin filament binding 0.707257679204688 bayes_pls_golite062009
tubulin binding 0.356901755730737 bayes_pls_golite062009
microtubule binding 0.291759739904529 bayes_pls_golite062009
hydrolase activity 0.28424525033024 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [430-657]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AARDPNVGIY ITHEEYLHLG LERLIQRFSC RQLYGLAVQA SMWMQIPCDW VYIQWAQTYI  60
   61 KQSSEPEEVV LDNIVKRLSS RKYISYEKIA RTAYQEGRLI LSTKLLDFEP LAKHQVMLLL 120
  121 NMEAYEQALK KVIETMDNNL IIYVVLQIKQ QMAIASFFQI LNEYPDAVKV YVEFAKKNDR 180
  181 KTLHDFFYQD DNKQGIAVLA VEDTLKTATV NQRITSLKSA AKVCSESK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [658-835]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELSLEEKCLG DEIKLLQLQQ TYEDQFTGNF VGLTVNEVVV KLIQINQTQR ANKLRSDFQI  60
   61 PEKRFAWLKL RALVAIRDWV QIEQWAGSMR RSPIGFEPFV TEILSAGNKK EAAKYIPRCT 120
  121 QLTTQEKVDM WVQVGDVKSA SEEAAKSKSG SVLGDLLERV QTMPESRFVQ NALDQLRR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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