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Protein Overview: vma13

General Information:
Name(s) found: vma13 / SPAC7D4.10 [Sanger Pombe]
Description(s) found:
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  • gi|7493154|pir||T39088 probable vacuolar h(+)-atpase subunit - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|4582200|emb|CAB16727.2| V-type ATPase subunit H (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114760|ref|NP_593848.1| V-type ATPase subunit H [Schizosaccharomyces pombe] [NCBI NR]
  • gi|12585394|sp|O14265.2|VATH_SCHPO RecName: Full=V-type proton ATPase subunit H; Short=V-ATPase subunit H; AltName: Full=Vacuolar proton pump subunit H; AltName: Full=V-ATPase 54 kDa subunit [NCBI NR]
  • V-type ATPase subunit H [Sanger Pombe]
  • V-type proton ATPase subunit H OS=Schizosaccharomyces pombe GN=vma13 PE=2 SV=2 [Swiss-Prot]
  • PUTATIVE VACUOLAR ATP SYNTHASE SUBUNIT H; V-TYPE ATPASE H SUBUNIT; VACUOLAR PROTON PUMP COMPONENT; V1 SECTOR: O14265; [pompepVF.fasta]
  • Vacuolar ATP synthase subunit H (EC 3.6.3.14) (V-ATPase H subunit) (Vacuolar proton pump H subunit) (V-ATPase 54 kDa subunit) [pompep4896]
  • |vma13||vacuolar ATP synthase subunit H (putative) [pompepnew.fasta]
  • |vma13||vacuolar ATP synthase (subunit H) (predicted)|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • putative vacuolar ATP synthase subunit H; V-type ATPase H subunit; vacuolar proton pump component; V1 sector [Schizosaccharomyces pombe]gi|4582200|emb|CAB16727.2| SPAC7D4.10 [Schizosaccharomyces pombe]gi|12585394|sp|O14265|VATH_SCHPO Vacuolar ATP syntha [nrdb_11152004_Chlamydomonas]
  • |vma13||vacuolar ATP synthase |Schizosaccharomyces pombe|chr 1|||Manual [pompep2242005.fasta]
  • (O14265) Vacuolar ATP synthase subunit H (EC 3.6.3.14) (V-ATPase H subunit) (Vacuolar proton pump H subunit) (V-ATPase 54 kDa subunit) [pompep4896_normal_reversed]
  • |vma13||V-type ATPase subunit H |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC7D4.10 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Vacuolar ATP synthase subunit H (V-ATPase H subunit) (Vacuolar proton pump subunit H) (V-ATPase 54 kDa subunit) [nr-271106-contam.fasta]
  • SPAC7D4.10 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • |vma13||V-type ATPase V1 subunit H |Schizosaccharomyces pombe|chr 1|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • V-type proton ATPase subunit H OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=vma13 PE=3 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 450 amino acids

    Gene Ontology:
    Cellular Component: vacuolar proton-transporting V-type ATPase, V1 domain [IEA]
    vacuolar proton-transporting V-type ATPase complex [ICLink to PubMed article]
    Biological Process: ATP hydrolysis coupled proton transport [ICLink to PubMed article]
    vacuolar acidification [TASLink to PubMed article]
    ATP synthesis coupled proton transport [IEA]
    Molecular Function: ATP binding [ICLink to PubMed article]
    proton-transporting ATPase activity, rotational mechanism [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSDLELSN AASPPPVELD NSQVDEIINN VRCVAIPWQG YQRSGSLEEN ELQEIENLTG  60
   61 KPLSAYVKTA EEDTTAYSNL FLKLLSMKDT PDVVNFALVK LADTLLNSNK FLSAFGPAFY 120
  121 DFLEKDESYI NYLDDDSKLL FARVFALCSS SSPCSVAKAF TLFLEYLGKL MQSLNPLTRL 180
  181 FAVQCLNGVL TLKAHRYALW AENTCSFRLA ELLRNSIGDT QLQYYSLFCF WQLTFESHIA 240
  241 QDINKRFDLI KLLVQIIRSD TKTKVYRLVL AILVNLIDKA PKDTISTMLL EHVDKAVQLL 300
  301 QKRKWADEDI TNYLDFITST LDESSKHLST FDMYKSELDT GILHWSPSHR SEDFWHQNAK 360
  361 RLNEDNYALL KKLFHIVQYN EDNTSLAVAC HDLGAYIRSY PEGRSLIIKY GAKQRIMDLM 420
  421 SHPDPEVRFE ALSTVQLLMT EVCFLSKITL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..450] PSI-BLAST 97.045757 Regulatory subunit H of the V-type ATPase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrogen ion transmembrane transporter activity
    		•  8.27793692177437 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  6.61991113486273 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  5.91856058767561 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  3.08652472111805 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.01705909078235 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.62570967627286 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.5665080711484 bayes_pls_golite062009
  • transporter activity
    		•  2.48700774379895 bayes_pls_golite062009
  • binding
    		•  2.4389817190572 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.26725422172281 bayes_pls_golite062009
  • protein transporter activity
    		•  1.76605071606564 bayes_pls_golite062009
  • protein binding
    		•  1.63705839411934 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  1.60849969922683 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.28481004323799 bayes_pls_golite062009
  • clathrin binding
    		•  0.53271167669517 bayes_pls_golite062009
  • hydrolase activity
    		•  0.528047226063932 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.252495966234234 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.226380819487924 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.221901941018475 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.217517113570989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.178770060806735 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.175241020572885 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.174922130116569 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.100181463251306 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  0.0949889863173228 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0635404099346928 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0548082069333885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.052195223119721 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle