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Protein Overview: ulp2

General Information:
Name(s) found: ulp2 / SPAC17A5.07c [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • SUMO deconjugating cysteine peptidase Ulp2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 652 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: protein desumoylation [ISSLink to PubMed article]
    chromosome condensation [ISSLink to PubMed article]
    proteolysis [IEA]
    Molecular Function: SUMO-specific protease activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPWMINQGHS LVFFPRLENK GLTLPRLLIH IPILIFLQSR GTSPNDAIPI KSPLERLANS  60
   61 VTSPEKPTVR TAIQKDSPRR KQIDDDQTPP KHLKRSFQNV TVVSPRKKKT IDVVELPFTK 120
  121 GGYGGFYDPR PGCLKFTTHE INVSYTDTSI PVIHIPVQLL KRCCWLQGWR DNLVESPVHA 180
  181 IHLTLKNRDM KRITIGDSAS LLFLYNPLHV ESARAGLDLL DQSDFSLTSP SSAKEFKQLL 240
  241 TLKQSTIIPR TPQKTVRSIV KQTSSPHSSK MPKHSLPSSP TPFNSNSGDS LLSRIKNSNQ 300
  301 SSSERPTANN GAQEQNQSSS SAGNTSNDFS TLCSQGSDKT LLSDASCTTI LVYPFSGTNS 360
  361 IAITNTDLTR LNEGEFLNDT IVDFYLRYLY CKLQTQNPSL ANDTHIFNTF FYNRLTSKDK 420
  421 DGKRLGHRGV RKWTQKVDLF HKKYIIVPIN ETFHWYLAII CNIDRLMPVD TKLEEQDEIV 480
  481 MSSVEQPSAS KTRQAELTSN SPAILIFDSL ANLHKGALNY LREYLLEEAF ERKNVHLKST 540
  541 DIRGFHAKVP QQSNFSDCGI YALHFVELFL ETPEQVIANT LDKSLRRTDA KNFDQQWNLQ 600
  601 KINTMRCDLK GLIRRLSTEW SSNNERQSLS SGSNDEEDKE NDDDLAILPI TN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..267] deduced N/A No confident structure predictions are available.
    2 View Details [268..652] PSI-BLAST 53.30103 Structure of human Senp2 in complex with SUMO-1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • cysteine-type peptidase activity
    		•  6.54685807643041 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  6.39247995905454 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  5.52987342617304 bayes_pls_golite062009
  • SUMO-specific protease activity
    		•  4.63546214004196 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  3.91170685383331 bayes_pls_golite062009
  • thiolester hydrolase activity
    		•  2.1617608442198 bayes_pls_golite062009
  • binding
    		•  1.77258741259391 bayes_pls_golite062009
  • peptidase activity
    		•  1.2363147273892 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.10408384086394 bayes_pls_golite062009
  • protein binding
    		•  1.08139200376412 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • hydrolase activity
    		•  0.785819892845781 bayes_pls_golite062009
  • NEDD8-specific protease activity
    		•  0.687958315289315 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.439226369799415 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.366512660710683 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  0.352657819388643 bayes_pls_golite062009
  • DNA binding
    		•  0.168761518285256 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.144331158319621 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle