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Protein Overview: sfc2

General Information:
Name(s) found: sfc2 / SPAC144.09c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • RNA polymerase III transcription factor TFIIIA [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 374 amino acids

    Gene Ontology:
    Cellular Component: transcription factor complex [ISSLink to PubMed article]
    nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: transcription initiation from RNA polymerase III promoter [TASLink to PubMed article]
    regulation of transcription [ICLink to PubMed article]
    Molecular Function: DNA binding [IEA]
    zinc ion binding [IEA]
    RNA binding [IEA]
    RNA polymerase III transcription factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCHFNELSIE IESKNLRSAK KIFHCPYEEC GKKYSRPSLL EQHLRTHSNE RPFVCDYTGC  60
   61 SKAFYRKSHL KIHKRCHTNV KPFSCHYDGC DAQFYTQQHL ERHIEVHRKP KPYACTWEGC 120
  121 DECFSKHQQL RSHISACHTH LLPYPCTYQD CELRFATKQK LQNHVNRAHE KIISYSCPHE 180
  181 SCVGHEGFEK WSQLQNHIRE AHVPSCSICG RQFKTAAHLR HHVVLHQTTL EERKTYHCPM 240
  241 EGCKKSFTRS SALKKHISVI HEGNMAFHCD SCGTKFGYKH MLQRHLERGT CKKAHKPYIN 300
  301 ECGIKHDGIE GVAIHDQKEK ELSSNLVSDV AKKIINEVTG HGYKEAREYS CSFPECNYRF 360
  361 KRLYDMHRHL NSHH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..183] PSI-BLAST 22.0 Transcription factor IIIA, TFIIIA
    2 View Details [184..374] PSI-BLAST 40.39794 No description for 2i13A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • transcription activator activity
    		•  2.19952417915035 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.42975942698743 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • protein binding
    		•  1.00484935878505 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.912796194488319 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.240825841910931 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.0129353639725593 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle