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View Structure Prediction Details

Protein: sfc2
Organism: Schizosaccharomyces pombe
Length: 374 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sfc2.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
493.0 [0..3] [373..2528]
gi|2224593 - gi|2224593|dbj|BAA20784.1| KIAA0326 [Homo sapiens]
424.0 [0..3] [373..216]
gi|114679322 - gi|114679322|ref|XP_512927.2| PREDICTED: zinc finger protein 71 [Pan troglodytes]
421.0 [0..4] [373..312]
gi|109128254 - gi|109128254|ref|XP_001102645.1| PREDICTED: similar to zinc finger protein 629 [Macaca mulatta]
420.0 [0..3] [373..209]
gi|76653675 - gi|76653675|ref|XP_872180.1| PREDICTED: zinc finger protein 629 [Bos taurus]
414.0 [0..3] [373..158]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCHFNELSIE IESKNLRSAK KIFHCPYEEC GKKYSRPSLL EQHLRTHSNE RPFVCDYTGC  60
   61 SKAFYRKSHL KIHKRCHTNV KPFSCHYDGC DAQFYTQQHL ERHIEVHRKP KPYACTWEGC 120
  121 DECFSKHQQL RSHISACHTH LLPYPCTYQD CELRFATKQK LQNHVNRAHE KIISYSCPHE 180
  181 SCV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.0
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
transcription repressor activity 3.27542149084008 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
transcription activator activity 2.19952417915035 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
sequence-specific DNA binding 1.42975942698743 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
transcription corepressor activity 1.34049786451995 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
transcription coactivator activity 0.912796194488319 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
structure-specific DNA binding 0.240825841910931 bayes_pls_golite062009
double-stranded DNA binding 0.0129353639725593 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [184-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHEGFEKWSQ LQNHIREAHV PSCSICGRQF KTAAHLRHHV VLHQTTLEER KTYHCPMEGC  60
   61 KKSFTRSSAL KKHISVIHEG NMAFHCDSCG TKFGYKHMLQ RHLERGTCKK AHKPYINECG 120
  121 IKHDGIEGVA IHDQKEKELS SNLVSDVAKK IINEVTGHGY KEAREYSCSF PECNYRFKRL 180
  181 YDMHRHLNSH H

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.39794
Match: 2i13A
Description: No description for 2i13A was found.

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