Protein Overview: cct8

General Information:
Name(s) found:	cct8 / SPBC337.05c [Sanger Pombe]
Description(s) found: SHOW ONLY BEST	pir\|\|T40258 probable t-complex protein 1, theta subunit - fission yeast (Schizosaccharomyces pombe) [NCBI NR] gi\|3738182\|emb\|CAA21275.1\| chaperonin-containing T-complex theta subunit Cct8 [Schizosaccharomyces pombe] [NCBI NR] gi\|19112198\|ref\|NP_595406.1\| chaperonin-containing T-complex theta subunit Cct8 (predicted) [Schizosaccharomyces pombe] [NCBI NR] gi\|12644353\|sp\|P78921.3\|TCPQ_SCHPO RecName: Full=Probable T-complex protein 1 subunit theta; Short=TCP-1-theta; AltName: Full=CCT-theta [NCBI NR] chaperonin-containing T-complex theta subunit Cct8 [Sanger Pombe] Probable T-complex protein 1 subunit theta OS=Schizosaccharomyces pombe GN=cct8 PE=2 SV=3 [Swiss-Prot] T-COMPLEX PROTEIN 1, THETA SUBUNIT: O74816;P78921; [pompepVF.fasta] Probable T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta) [pompep4896] \|cct8\|\|putative t-complex protein 1, theta subunit [pompepnew.fasta] \|cct8\|\|chaperonin-containing T-complex\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [pombe041504.fasta] probable t-complex protein 1, theta subunit [Schizosaccharomyces pombe]gi\|3738182\|emb\|CAA21275.1\| cct8 [Schizosaccharomyces pombe]gi\|12644353\|sp\|P78921\|TCPQ_SCHPO Probable T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta)gi\|7493022\|pir\|\|T402 [nrdb_11152004_Chlamydomonas] (P78921) Probable T-complex protein 1, theta subunit (TCP-1-theta) (CCT-theta) [pompep4896_normal_reversed] \|cct8\|\|chaperonin-containing T-complex theta subunit Cct8\|Schizosaccharomyces pombe\|chr 2\|\|\|Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta] Probable T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) [nr-271106-contam.fasta] T-complex protein 1 subunit theta [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta] SPBC337.05c [Schizosaccharomyces pombe] [nr-271106-contam.fasta] Probable T-complex protein 1 subunit theta OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cct8 PE=2 SV=3 [uniprot_sprot.fasta.20160308]
Organism:	Schizosaccharomyces pombe
Length:	546 amino acids
Gene Ontology:
Cellular Component:	chaperonin-containing T-complex [IDA] cytoskeleton [ISS] cytoplasm [ISS] cytosol [IDA]
Biological Process:	tubulin complex assembly [IC] cytoskeleton organization [ISS] protein folding [ISS]
Molecular Function:	ATP binding [IEA] unfolded protein binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRVPKASG PQLFREGYRI MQGVEDAVIR NCNAIRELSE ITRTSLGPNG KNKIVVNHLQ  60
   61 QTFLTNDAAT IIRELEVIHP AAKLVVDATQ QQENELGDAA NFVVVFTGEL LAKAENMIRM 120
  121 GLTPLEIAKG YEMALSHTME VLEEICADKI ETVESEKELI KAIRTCISSK QYGNEDFLSD 180
  181 LVAKAILTVL PKDPSKFNVD NIRVVKIMGS SLYNSQVVKG MVFPREPEGT VTRSKEAKVA 240
  241 VFSCPLDISQ TETKGTVLLH NAQEMLDFSK GEENLIESHI KEIYDAGVRV VVTSGNVNDL 300
  301 VLHYLNRFEI LVIRVPSKFE LRRLCRVVGA TPLARMGVPM PEEMGSVDVV ETIEIGGDRV 360
  361 TVFRQVEDIT RTATIVLRGA TKTYLDDLER AIDDGVNIVK ALVKDNRLIF GAGASDMQLC 420
  421 IRLISVGEKT PGIYQHAIKQ YGEAFEVVPR TISENAGLDP TDVISKLYAA HHKENGESIG 480
  481 VDVECENDGT LDAKEAGIFD VLLAKKSAIR LATETVLTVL NVDQVVMSKP AGGPKPPGPN 540
  541 PHWDDD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
unfolded protein binding	9.9038451294995	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	3.6934849790316	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	3.40373598585301	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	3.28982639907979	bayes_pls_golite062009
binding	3.11215702001989	bayes_pls_golite062009
protein binding	2.03574683256805	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.88769858570433	bayes_pls_golite062009
ATPase activity	1.85640607183492	bayes_pls_golite062009
pyrophosphatase activity	1.81343301131567	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.79412354283105	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.79183933227438	bayes_pls_golite062009
nucleic acid binding	1.67284737458957	bayes_pls_golite062009
DNA binding	1.60256620441721	bayes_pls_golite062009
transporter activity	1.27879339110564	bayes_pls_golite062009
transmembrane transporter activity	1.08697283907212	bayes_pls_golite062009
chaperone binding	0.91200031047441	bayes_pls_golite062009
substrate-specific transporter activity	0.828920415160435	bayes_pls_golite062009
hydrolase activity	0.577900060851977	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.573106450426516	bayes_pls_golite062009
ATPase activity, coupled	0.527748436977659	bayes_pls_golite062009
ion transmembrane transporter activity	0.280310103153739	bayes_pls_golite062009
active transmembrane transporter activity	0.275534581026027	bayes_pls_golite062009
hydrogen-exporting ATPase activity, phosphorylative mechanism	0.26275673855778	bayes_pls_golite062009
primary active transmembrane transporter activity	0.252704226951294	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.243984617084631	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.205808843369749	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.202279803135899	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.20198255686005	bayes_pls_golite062009
transferase activity	0.18639662517366	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.16424934648837	bayes_pls_golite062009
catalytic activity	0.107125378994589	bayes_pls_golite062009
kinase activity	0.0871496920547826	bayes_pls_golite062009
cation transmembrane transporter activity	0.0778814959589007	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..546]	PSI-BLAST	139.0	Crystal structure of the chaperonin from Thermococcus strain KS-1 (nucleotide-free form of single mutant)

Protein Overview: cct8

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: