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Protein Overview: tub1

General Information:
Name(s) found: tub1 / SPBC800.05c [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • tubulin alpha 2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 449 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    microtubule [TASLink to PubMed article]
    Biological Process: protein polymerization [IEA]
    mitochondrion distribution [IMPLink to PubMed article]
    establishment or maintenance of cell polarity [IMPLink to PubMed article]
    microtubule cytoskeleton organization [ICLink to PubMed article]
    microtubule-based movement [IEA]
    Molecular Function: GTP binding [ICLink to PubMed article]
    protein heterodimerization activity [IPILink to PubMed article]
    GTPase activity [IEA]
    structural constituent of cytoskeleton [ICLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREIISIHVG QAGTQIGNAC WELYCLEHGI QPNGYMNPET ASQNSDGGFS TFFSETGQGK  60
   61 YVPRSIYVDL EPNVIDQVRT GPYRDLFHPE QLITGKEDAS NNYARGHYTV GKELVDEVTD 120
  121 KIRRIADNCS GLQGFLVFHS FGGGTGSGFG ALLLERLAME YTKKSKLQFS VYPAPQVSTS 180
  181 VVEPYNSVLT THATLDLADC TFMVDNESCY DICRRNLDIE RPSYENLNRL IAQVVSSITA 240
  241 SLRFEGSLNV DLAEFQTNLV PYPRIHFPLV TYAPIVSAAK AFHESNSVQE ITNQCFEPYN 300
  301 QMVKCDPRAG RYMATCLLYR GDVIPRDVQA AVTTIKAKRT IQFVDWCPTG FKIGICDRPP 360
  361 QHIEGSEIAK VDRAVCMLSN TTSIAEAWSR LDHKFDLMYS KRAFVHWYVG EGMEEGEFSE 420
  421 AREDLAALER DYEEVGQDSM EVDYMEEEY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..449] PSI-BLAST 1000.0 Tubulin-colchicine-vinblastine: stathmin-like domain complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of cytoskeleton
    		•  4.04224160177678 bayes_pls_golite062009
  • structural molecule activity
    		•  3.32779015200848 bayes_pls_golite062009
  • tubulin binding
    		•  2.4432045213385 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.24606230377981 bayes_pls_golite062009
  • binding
    		•  2.00508289492248 bayes_pls_golite062009
  • GTPase activity
    		•  1.87512665946067 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.77500173070686 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.7017047947554 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.68267378160702 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.68038087466376 bayes_pls_golite062009
  • protein binding
    		•  1.60795853516357 bayes_pls_golite062009
  • MHC class I protein binding
    		•  1.46574865275013 bayes_pls_golite062009
  • gamma-tubulin binding
    		•  1.02742779831447 bayes_pls_golite062009
  • hydrolase activity
    		•  0.502038132260603 bayes_pls_golite062009
  • receptor binding
    		•  0.00945891657658993 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle