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Interacting selectively and non-covalently with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. Interacting selectively and non-covalently with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation. Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. Interacting selectively with major histocompatibility complex class I molecules via the lateral surface. Interacting selectively with major histocompatibility complex class I molecules via the antigen binding groove.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: MHC class I protein binding
Acc: GO:0042288
Aspect: Molecular Function
Desc: Interacting selectively and non-covalently with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
Synonyms:
  • major histocompatibility complex class I binding
  • gamma-delta T cell receptor activity
  • major histocompatibility complex class I ligand
  • alpha-beta T cell receptor activity
  • T cell receptor activity
Proteins in PDR annotated with:
   This term: 15 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042288 - MHC class I protein binding (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle