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Protein Overview: spt3

General Information:
Name(s) found: spt3 / SPCC61.02 [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • histone acetyltransferase complex subunit Spt3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 307 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    chromatin [RCALink to PubMed article]
    SAGA complex [ISSLink to PubMed article]
    Biological Process: chromatin remodeling [IC]
    histone acetylation [ISSLink to PubMed article]
    regulation of transcription [ICLink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [ISS]
    Molecular Function: DNA binding [IEA]
    transcription cofactor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTETGRTSKY RVEIQQMMFI LGEVQDPLPE TTQLVEELIR GQVMEMLIQA NELALRRGSR  60
   61 SITVEDLFFL IRHDRAKVNR LKTYLSWKEV RKKAKEQDAN PADTKDLFEE VDSKTRSMNA 120
  121 VAMPWEVKNM FTEPVPETEE FEEDNDTMEM AYATRQRLKM ADERTKKMTR EEYVHWSECR 180
  181 QASFTYRKGK RFREWCGMSI LTDTRPDNDI VDILGFLTFE IVATLTEEAL AVKDRMDRIQ 240
  241 NSSGSGGSHA AHHPKNCSLF DGLTEGRTPL QVSHVLEAFR RLQIPDKTHT AMRSFHGGLV 300
  301 KSRVYLI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] FFAS03 1.05 Negative cofactor 2, NC2, beta chain
    2 View Details [161..307] FFAS03 1.61 TAF(II)28

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  6.26683920136262 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  5.93249134612505 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  5.93249134612505 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.49084162254966 bayes_pls_golite062009
  • DNA binding
    		•  4.24660531286828 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  4.2172829451557 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.14026521609645 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.91807454227165 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.91533222675137 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.38996237245502 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.35419529667223 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.18312128320637 bayes_pls_golite062009
  • binding
    		•  3.14832737946099 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.02428691626433 bayes_pls_golite062009
  • transcription factor activity
    		•  2.39322722597434 bayes_pls_golite062009
  • transcription activator activity
    		•  1.12739348005764 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.03060091158028 bayes_pls_golite062009
  • protein binding
    		•  1.01897642648285 bayes_pls_golite062009
  • transcription factor binding
    		•  1.01773884290535 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.976797801726735 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.840442755533537 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  0.718301463460921 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.621482805601238 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.450418553112188 bayes_pls_golite062009
  • histone binding
    		•  0.184823910505751 bayes_pls_golite062009
  • transferase activity
    		•  0.137803992484684 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0585868733603467 bayes_pls_golite062009
    2
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  6.26683920136262 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  5.93249134612505 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  5.93249134612505 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.49084162254966 bayes_pls_golite062009
  • DNA binding
    		•  4.24660531286828 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  4.2172829451557 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.14026521609645 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.91807454227165 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.91533222675137 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.38996237245502 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.35419529667223 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.18312128320637 bayes_pls_golite062009
  • binding
    		•  3.14832737946099 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.02428691626433 bayes_pls_golite062009
  • transcription factor activity
    		•  2.39322722597434 bayes_pls_golite062009
  • transcription activator activity
    		•  1.12739348005764 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.03060091158028 bayes_pls_golite062009
  • protein binding
    		•  1.01897642648285 bayes_pls_golite062009
  • transcription factor binding
    		•  1.01773884290535 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.976797801726735 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.840442755533537 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  0.718301463460921 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.621482805601238 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.450418553112188 bayes_pls_golite062009
  • histone binding
    		•  0.184823910505751 bayes_pls_golite062009
  • transferase activity
    		•  0.137803992484684 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0585868733603467 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle