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View Structure Prediction Details

Protein: spt3
Organism: Schizosaccharomyces pombe
Length: 307 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for spt3.

Description E-value Query
Range
Subject
Range
gi|2253303 - gi|2253303|gb|AAC49995.1| Spt3 [Schizosaccharomyces pombe]
435.0 [0..1] [307..1]
gi|4929173 - gi|4929173|gb|AAD33888.1|AF142757_1 transcription factor Spt3 [Candida albicans]
gi|46441197, gi|... - gi|68473155|ref|XP_719383.1| hypothetical protein CaO19.7622 [Candida albicans SC5314], gi|46441197|...
gi|238880407 - gi|238880407|gb|EEQ44045.1| protein SPT3 [Candida albicans WO-1]
384.0 [0..4] [307..3]
gi|151942367 - gi|151942367|gb|EDN60723.1| histone acetyltransferase SAGA complex member [Saccharomyces cerevisiae ...
gi|45719800, gi|... - gi|45719802|emb|CAE52119.1| Spt3p [Saccharomyces cerevisiae], gi|45719800|emb|CAE52118.1| Spt3p [Sac...
383.0 [0..7] [307..4]
gi|39952247, gi|... - gi|39952247|ref|XP_363840.1| hypothetical protein MGG_01766 [Magnaporthe grisea 70-15], gb|EAA56115....
375.0 [0..5] [306..6]
gi|49657420, gi|... - gi|50426307|ref|XP_461750.1| hypothetical protein DEHA0G05346g [Debaryomyces hansenii CBS767], gi|49...
374.0 [0..1] [307..1]
gi|83770515 - gi|83770515|dbj|BAE60648.1| unnamed protein product [Aspergillus oryzae]
gi|169763174 - gi|169763174|ref|XP_001727487.1| hypothetical protein [Aspergillus oryzae RIB40]
372.0 [0..3] [306..2]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTETGRTSKY RVEIQQMMFI LGEVQDPLPE TTQLVEELIR GQVMEMLIQA NELALRRGSR  60
   61 SITVEDLFFL IRHDRAKVNR LKTYLSWKEV RKKAKEQDAN PADTKDLFEE VDSKTRSMNA 120
  121 VAMPWEVKNM FTEPVPETEE FEEDNDTMEM AYATRQRLKM 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 1jfiB
Description: Negative cofactor 2, NC2, beta chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 6.26683920136262 bayes_pls_golite062009
lysine N-acetyltransferase activity 5.93249134612505 bayes_pls_golite062009
histone acetyltransferase activity 5.93249134612505 bayes_pls_golite062009
N-acetyltransferase activity 4.49084162254966 bayes_pls_golite062009
DNA binding 4.24660531286828 bayes_pls_golite062009
N-acyltransferase activity 4.2172829451557 bayes_pls_golite062009
nucleic acid binding 4.14026521609645 bayes_pls_golite062009
transcription regulator activity 3.91807454227165 bayes_pls_golite062009
acetyltransferase activity 3.91533222675137 bayes_pls_golite062009
acyltransferase activity 3.38996237245502 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.35419529667223 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.18312128320637 bayes_pls_golite062009
binding 3.14832737946099 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.02428691626433 bayes_pls_golite062009
transcription factor activity 2.39322722597434 bayes_pls_golite062009
transcription activator activity 1.12739348005764 bayes_pls_golite062009
nucleotidyltransferase activity 1.03060091158028 bayes_pls_golite062009
protein binding 1.01897642648285 bayes_pls_golite062009
transcription factor binding 1.01773884290535 bayes_pls_golite062009
transcription coactivator activity 0.976797801726735 bayes_pls_golite062009
transcription cofactor activity 0.840442755533537 bayes_pls_golite062009
transcription initiation factor activity 0.718301463460921 bayes_pls_golite062009
transcription repressor activity 0.621482805601238 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.450418553112188 bayes_pls_golite062009
histone binding 0.184823910505751 bayes_pls_golite062009
transferase activity 0.137803992484684 bayes_pls_golite062009
sequence-specific DNA binding 0.0585868733603467 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [161-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADERTKKMTR EEYVHWSECR QASFTYRKGK RFREWCGMSI LTDTRPDNDI VDILGFLTFE  60
   61 IVATLTEEAL AVKDRMDRIQ NSSGSGGSHA AHHPKNCSLF DGLTEGRTPL QVSHVLEAFR 120
  121 RLQIPDKTHT AMRSFHGGLV KSRVYLI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.61
Match: 1bh8B
Description: TAF(II)28
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 6.26683920136262 bayes_pls_golite062009
lysine N-acetyltransferase activity 5.93249134612505 bayes_pls_golite062009
histone acetyltransferase activity 5.93249134612505 bayes_pls_golite062009
N-acetyltransferase activity 4.49084162254966 bayes_pls_golite062009
DNA binding 4.24660531286828 bayes_pls_golite062009
N-acyltransferase activity 4.2172829451557 bayes_pls_golite062009
nucleic acid binding 4.14026521609645 bayes_pls_golite062009
transcription regulator activity 3.91807454227165 bayes_pls_golite062009
acetyltransferase activity 3.91533222675137 bayes_pls_golite062009
acyltransferase activity 3.38996237245502 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.35419529667223 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.18312128320637 bayes_pls_golite062009
binding 3.14832737946099 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.02428691626433 bayes_pls_golite062009
transcription factor activity 2.39322722597434 bayes_pls_golite062009
transcription activator activity 1.12739348005764 bayes_pls_golite062009
nucleotidyltransferase activity 1.03060091158028 bayes_pls_golite062009
protein binding 1.01897642648285 bayes_pls_golite062009
transcription factor binding 1.01773884290535 bayes_pls_golite062009
transcription coactivator activity 0.976797801726735 bayes_pls_golite062009
transcription cofactor activity 0.840442755533537 bayes_pls_golite062009
transcription initiation factor activity 0.718301463460921 bayes_pls_golite062009
transcription repressor activity 0.621482805601238 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.450418553112188 bayes_pls_golite062009
histone binding 0.184823910505751 bayes_pls_golite062009
transferase activity 0.137803992484684 bayes_pls_golite062009
sequence-specific DNA binding 0.0585868733603467 bayes_pls_golite062009

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