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Protein Overview: reb1

General Information:
Name(s) found: reb1 / SPBC1198.11c [Sanger Pombe]
Description(s) found:
Found 15 descriptions.
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  • RNA polymerase I transcription termination factor Reb1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 504 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    nucleolus [RCALink to PubMed article]
    Biological Process: replication fork arrest at rDNA repeats [IMPLink to PubMed article]
    termination of RNA polymerase I transcription [IMPLink to PubMed article]
    regulation of transcription termination [ICLink to PubMed article]
    Molecular Function: rDNA spacer replication fork barrier binding [TASLink to PubMed article]
    RNA polymerase I transcription termination factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTSVLNPEL QIHGFIGVDS LQSSRKRKND FDDFPLNKGL KTNNNDYSGS IEPKFSPALS  60
   61 IKEDGKNDRN FEALMSLQAQ DSNLSEQNTS IHLDALASSS IALGNDNVDS SAFLSKVNKG 120
  121 VNAMRNSTSN QTNDSILISP SEITNMDPFL KGSARWTAEH WDYLERRMQN FCQTYSLDHT 180
  181 QVADSLHEKR LHGPLSSLVK LLVQEMPSFT RRTILRHLRA LYNIPGYEKY SRKNSSGRGD 240
  241 FGVQETAIIS QEVHNFIMDQ GWSEYQFCNQ IWAGKCPKTI RMFYSNLYKK LSHRDAKSIY 300
  301 HHVRRAYNPF EDRCVWSKEE DEELRKNVVE HGKCWTKIGR KMARMPNDCR DRWRDVVRFG 360
  361 DKLKRNAWSL EEETQLLQIV AELRNREDLS SDINWTLVAQ MLGTRTRLQC RYKFQQLTKA 420
  421 ASKFELQENV WLLERIYDSL LNNGGKIHWE NIVKEANGRW TRDQMLFQFI NLKKMIPSYD 480
  481 NLPLLEATKS AIDDFKVVLS GFSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..167] MSA 2.079983 View MSA. No confident structure predictions are available.
    2 View Details [168..360] PSI-BLAST 36.154902 c-Myb, DNA-binding domain
    3 View Details [361..504] FFAS03 4.26 c-Myb, DNA-binding domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.48167085416403 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.20953772435302 bayes_pls_golite062009
  • transcription factor activity
    		•  3.86239731611043 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.36647648239063 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.3674112578735 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.04108499638264 bayes_pls_golite062009
  • chromatin binding
    		•  0.876241359231159 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • histone binding
    		•  0.0391625783266718 bayes_pls_golite062009
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  4.86538715425734 bayes_pls_golite062009
  • DNA binding
    		•  4.21984077606009 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.98153794570167 bayes_pls_golite062009
  • transcription factor activity
    		•  3.58468334639092 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.14300374130294 bayes_pls_golite062009
  • binding
    		•  2.92574888336072 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.15328641013602 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.00875399167309 bayes_pls_golite062009
  • transcription activator activity
    		•  1.5973137667873 bayes_pls_golite062009
  • transcription factor binding
    		•  1.24678737091956 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.18041819525443 bayes_pls_golite062009
  • protein binding
    		•  0.795494287543952 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.758137852714052 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.691780246385357 bayes_pls_golite062009
  • chromatin binding
    		•  0.65622150362507 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle