YRC Public Data Repository - Protein Structure Prediction

Protein:	reb1
Organism:	Schizosaccharomyces pombe
Length:	504 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for reb1.

Description	E-value	Query Range	Subject Range
gi\|4049500, gi\|7... - gi\|7522515\|pir\|\|T40613 probable myb like dna-binding protein - fission yeast (Schizosaccharomyces p...	329.0	[0..1]	[462..1]
gi\|9294065, gi\|1... - gi\|9294065\|dbj\|BAB02022.1\| unnamed protein product [Arabidopsis thaliana], gi\|18401769\|ref\|NP_566597...	226.0	[0..33]	[392..328]
gi\|114614304 - gi\|114614304\|ref\|XP_001161927.1\| PREDICTED: cyclin D binding myb-like transcription factor 1 isoform...	215.0	[0..129]	[499..2]
gi\|48976051, gi\|... - gi\|48976051\|ref\|NP_066968.2\| cyclin D binding myb-like transcription factor 1 [Homo sapiens], gi\|476...	202.0	[0..129]	[499..2]
gi\|109067615, gi... - gi\|109067619\|ref\|XP_001107342.1\| PREDICTED: similar to cyclin D binding myb-like transcription facto...	202.0	[0..129]	[499..2]

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Predicted Domain #1

Region A:
Residues: [1-167]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTSVLNPEL QIHGFIGVDS LQSSRKRKND FDDFPLNKGL KTNNNDYSGS IEPKFSPALS  60
   61 IKEDGKNDRN FEALMSLQAQ DSNLSEQNTS IHLDALASSS IALGNDNVDS SAFLSKVNKG 120
  121 VNAMRNSTSN QTNDSILISP SEITNMDPFL KGSARWTAEH WDYLERR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [168-360]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNFCQTYSL DHTQVADSLH EKRLHGPLSS LVKLLVQEMP SFTRRTILRH LRALYNIPGY  60
   61 EKYSRKNSSG RGDFGVQETA IISQEVHNFI MDQGWSEYQF CNQIWAGKCP KTIRMFYSNL 120
  121 YKKLSHRDAK SIYHHVRRAY NPFEDRCVWS KEEDEELRKN VVEHGKCWTK IGRKMARMPN 180
  181 DCRDRWRDVV RFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.154902
Match:	1h88C
Description:	c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	5.13863038737912	bayes_pls_golite062009
DNA binding	4.48167085416403	bayes_pls_golite062009
nucleic acid binding	4.20953772435302	bayes_pls_golite062009
transcription factor activity	3.86239731611043	bayes_pls_golite062009
transcription repressor activity	3.36647648239063	bayes_pls_golite062009
binding	3.02779747447702	bayes_pls_golite062009
sequence-specific DNA binding	2.41271657675151	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.26183812259792	bayes_pls_golite062009
transcription activator activity	1.77700860354597	bayes_pls_golite062009
transcription factor binding	1.40653841901929	bayes_pls_golite062009
transcription corepressor activity	1.3674112578735	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.04108499638264	bayes_pls_golite062009
chromatin binding	0.876241359231159	bayes_pls_golite062009
transcription cofactor activity	0.84983974758882	bayes_pls_golite062009
protein binding	0.830419844171551	bayes_pls_golite062009
histone binding	0.0391625783266718	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [361-504]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKLKRNAWSL EEETQLLQIV AELRNREDLS SDINWTLVAQ MLGTRTRLQC RYKFQQLTKA  60
   61 ASKFELQENV WLLERIYDSL LNNGGKIHWE NIVKEANGRW TRDQMLFQFI NLKKMIPSYD 120
  121 NLPLLEATKS AIDDFKVVLS GFSN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.26
Match:	1h88C
Description:	c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.86538715425734	bayes_pls_golite062009
DNA binding	4.21984077606009	bayes_pls_golite062009
nucleic acid binding	3.98153794570167	bayes_pls_golite062009
transcription factor activity	3.58468334639092	bayes_pls_golite062009
transcription repressor activity	3.14300374130294	bayes_pls_golite062009
binding	2.92574888336072	bayes_pls_golite062009
sequence-specific DNA binding	2.15328641013602	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.00875399167309	bayes_pls_golite062009
transcription activator activity	1.5973137667873	bayes_pls_golite062009
transcription factor binding	1.24678737091956	bayes_pls_golite062009
transcription corepressor activity	1.18041819525443	bayes_pls_golite062009
protein binding	0.795494287543952	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.758137852714052	bayes_pls_golite062009
transcription cofactor activity	0.691780246385357	bayes_pls_golite062009
chromatin binding	0.65622150362507	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: