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Protein Overview: rad21

General Information:
Name(s) found: rad21 / SPCC338.17c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • kleisin [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 628 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    mitotic cohesin complex [IDALink to PubMed article]
    condensed nuclear chromosome [ICLink to PubMed article]
    Biological Process: attachment of spindle microtubules to kinetochore [IMPLink to PubMed article]
    mitotic sister chromatid cohesion [IMPLink to PubMed article]
    double-strand break repair via homologous recombination [IGILink to PubMed article]
    double-strand break repair [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYSEAILSK KGPLAKVWLA AHWEKKLSKV QTLHTSIEQS VHAIVTEETA PMALRLSGQL  60
   61 MLGVVRIYSR KARYLLEDCT EALMRLKMSF QPGQVDMIEP ATALQSLKGK DAVTQSANLT 120
  121 LPETITEFDL LVPDSTFDFQ WSQLLRTPSR SSNTLELHSL PISSSPSFPS SQLSIEAGRN 180
  181 AQVESGFSLG ESFAHVGNDM QFHLPISNSG AATPRSVHSD NQSQISIEVG RDAPAAAATD 240
  241 LSGIIGPQMT KSPASSVTHF STPSMLPIGG TSLDDELLAP VDDLNLDLGL DDLLGDEQGA 300
  301 NAPAIEADEQ AETSSIHLPS DIMEDDSSRP AAAGVEEGQV VESATAPQQE KINPQKTVRR 360
  361 QRAIIDPVTE LSSKQMKKQL ADTSSITSPL CLNTSSIVFN ATVNFTRNGK FNTSIFSSNL 420
  421 NPKVNELLQA DFKQAILRKR KNESPEEVEP AKHQRTDTST ENQETAEVLD PEEIAAAELA 480
  481 NITEAAIATL PQETVVQPEG EAPELGSPMG FPVTALESAD DSLFDAPPVM LDEADLLGSE 540
  541 RLDSSVSEAL PSSQTAKDSL RNKWDPYTEG EKVSFQTLSA GCNREEAVQL FFDVLVLATK 600
  601 DVISVKQDVA IQNEITLTAK RGMLLSSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..132] Pfam 64.130768 No description for PF04825.4 was found. Confident ab initio structure predictions are available.
    2 View Details [133..319] MSA 2.135992 View MSA. No confident structure predictions are available.
    3 View Details [320..465] MSA 2.120993 View MSA. No confident structure predictions are available.
    4 View Details [466..628] PSI-BLAST 10.045757 Sc Smc1hd:Scc1-C complex, ATPgS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  3.74762577068811 bayes_pls_golite062009
  • DNA binding
    		•  3.6691593040775 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.56696430931691 bayes_pls_golite062009
  • binding
    		•  3.33026160538031 bayes_pls_golite062009
  • transcription factor activity
    		•  2.86565145658031 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.56454590328755 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.38449475025903 bayes_pls_golite062009
  • transcription activator activity
    		•  1.36544833032097 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.22911517186886 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.71350728967175 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.697234220778482 bayes_pls_golite062009
  • protein binding
    		•  0.653872239015235 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.349632742873003 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.300899564141452 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle