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View Structure Prediction Details

Protein: rad21
Organism: Schizosaccharomyces pombe
Length: 628 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rad21.

Description E-value Query
Range
Subject
Range
gi|73974375 - gi|73974375|ref|XP_861017.1| PREDICTED: similar to Double-strand-break repair protein rad21 homolog ...
428.0 [0..1] [625..1]
gi|74223149, gi|... - gi|74223149|dbj|BAE40713.1| unnamed protein product [Mus musculus], gi|74219960|dbj|BAE40560.1| unna...
424.0 [0..1] [625..1]
gi|71043766, gi|... - gi|71043766|ref|NP_001020872.1| RAD21 homolog [Rattus norvegicus], gi|68533861|gb|AAH99200.1| RAD21 ...
421.0 [0..1] [625..1]
gi|208965416 - gi|208965416|dbj|BAG72722.1| RAD21 homolog [synthetic construct]
gi|114621389, gi... - gi|114621399|ref|XP_001138797.1| PREDICTED: RAD21 homolog isoform 8 [Pan troglodytes], gi|114621397|...
RAD21 - RAD21 homolog (S. pombe)
418.0 [0..1] [625..1]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYSEAILSK KGPLAKVWLA AHWEKKLSKV QTLHTSIEQS VHAIVTEETA PMALRLSGQL  60
   61 MLGVVRIYSR KARYLLEDCT EALMRLKMSF QPGQVDMIEP ATALQSLKGK DAVTQSANLT 120
  121 LPETITEFDL LV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 64.130768
Match: PF04825.4
Description: No description for PF04825.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.831 0.038 double-strand break repair via homologous recombination a.24.13 Domain of the SRP/SRP receptor G-proteins

Predicted Domain #2
Region A:
Residues: [133-319]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDSTFDFQWS QLLRTPSRSS NTLELHSLPI SSSPSFPSSQ LSIEAGRNAQ VESGFSLGES  60
   61 FAHVGNDMQF HLPISNSGAA TPRSVHSDNQ SQISIEVGRD APAAAATDLS GIIGPQMTKS 120
  121 PASSVTHFST PSMLPIGGTS LDDELLAPVD DLNLDLGLDD LLGDEQGANA PAIEADEQAE 180
  181 TSSIHLP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [320-465]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDIMEDDSSR PAAAGVEEGQ VVESATAPQQ EKINPQKTVR RQRAIIDPVT ELSSKQMKKQ  60
   61 LADTSSITSP LCLNTSSIVF NATVNFTRNG KFNTSIFSSN LNPKVNELLQ ADFKQAILRK 120
  121 RKNESPEEVE PAKHQRTDTS TENQET

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [466-628]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEVLDPEEIA AAELANITEA AIATLPQETV VQPEGEAPEL GSPMGFPVTA LESADDSLFD  60
   61 APPVMLDEAD LLGSERLDSS VSEALPSSQT AKDSLRNKWD PYTEGEKVSF QTLSAGCNRE 120
  121 EAVQLFFDVL VLATKDVISV KQDVAIQNEI TLTAKRGMLL SSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.045757
Match: 1w1wE
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.74762577068811 bayes_pls_golite062009
DNA binding 3.6691593040775 bayes_pls_golite062009
nucleic acid binding 3.56696430931691 bayes_pls_golite062009
binding 3.33026160538031 bayes_pls_golite062009
transcription factor activity 2.86565145658031 bayes_pls_golite062009
sequence-specific DNA binding 1.56454590328755 bayes_pls_golite062009
structure-specific DNA binding 1.38449475025903 bayes_pls_golite062009
transcription activator activity 1.36544833032097 bayes_pls_golite062009
transcription repressor activity 1.22911517186886 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.71350728967175 bayes_pls_golite062009
DNA-dependent ATPase activity 0.697234220778482 bayes_pls_golite062009
protein binding 0.653872239015235 bayes_pls_golite062009
double-stranded DNA binding 0.349632742873003 bayes_pls_golite062009
DNA helicase activity 0.300899564141452 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle