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Protein Overview: erg12

General Information:
Name(s) found: erg12 / SPAC13G6.11c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • mevalonate kinase Erg12 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: ergosterol biosynthetic process [ISSLink to PubMed article]
    isoprenoid biosynthetic process [IEA]
    phosphorylation [IEA]
    Molecular Function: ATP binding [IEA]
    protein homodimerization activity [ISSLink to PubMed article]
    mevalonate kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSLIVSSP GKTILFGEHA VVYGATALAA AVSLRSYCKL QTTNNNEIVI VMSDIGTERR  60
   61 WNLQSLPWQH VTVENVQHPA SSPNLDLLQG LGELLKNEEN GLIHSAMLCT LYLFTSLSSP 120
  121 SQGCTLTISS QVPLGAGLGS SATISVVVAT SLLLAFGNIE PPSSNSLQNN KALALIEAWS 180
  181 FLGECCIHGT PSGIDNAVAT NGGLIAFRKA TAHQSAMKEF LKPKDTLSVM ITDTKQPKST 240
  241 KKLVQGVFEL KERLPTVIDS IIDAIDGISK SAVLALTSES DKNSSAKKLG EFIVLNQKLL 300
  301 ECLGVSHYSI DRVLQATKSI GWTKLTGAGG GGCTITLLTP ECKEEEFKLC KESLLAHKNS 360
  361 IYDVQLGGPG VSVVTDSDSF FPQYESDFDF KKLNLLSKFN KYYI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..404] PSI-BLAST 53.0 Mevalonate kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • binding
    		•  0.769835316275102 bayes_pls_golite062009
  • diphosphomevalonate decarboxylase activity
    		•  0.714132174817049 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.49664490095304 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.369771518688522 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.325699575011026 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.212099606954236 bayes_pls_golite062009
  • structural molecule activity
    		•  2.19428886088058E-4 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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