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Protein Overview: itr2

General Information:
Name(s) found: itr2 / SPAC20G8.03 [Sanger Pombe]
Description(s) found:
Found 15 descriptions.
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  • MFS myo-inositol transporter [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 557 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: transmembrane transport [IEA]
    myo-inositol transport [IMPLink to PubMed article]
    Molecular Function: myo-inositol transmembrane transporter activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFNNIPLAT IKSSDDKGKD FIVEMTTRPS ETKKKVPFSE DMREIPSLPN EEEANATDPQ  60
   61 ANEVADENGE GFEAEKISSW IWVLSAVAGI SGLLFGYDTG VISGALAVLG SDLGHVLSSG 120
  121 QKELITSATS FAALISATTS GWLADWVGRK RLLLCADAIF VIGSVIMAAS RNVAMMVVGR 180
  181 FIVGYGIGLT SLIVPMYITE LAPARLRGRL VIIYVVFITG GQLIAYSLNA AFEHVHQGWR 240
  241 IMFGIGAAPA LGQLISLFWT PESPRYLLRH NHVEKVYKIL SRIHPEAKPA EIAYKVSLIQ 300
  301 EGVKVDFPEG NKFQHFFHSL KVLFTVPSNR RSLFIGCFLQ WFQQFSGTNA IQYFSAIIFQ 360
  361 SVGFKNSISV SIVVGATNFV FTIVAFMFID RIGRRRILLC TSAVMIAGLA LCAIAYHFLP 420
  421 ADTTQNTNSG WQYVVLASII IFLASYASGI GNIPWQQAEL FPMEVRALGA GFSTAINWVG 480
  481 NLIISASFLT MMESITPTGT FALFAGFCFV GLVTSYFTYP ELAGMSIENI HKLLEKGFWQ 540
  541 AVKESTKRVR KGRIDEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..557] PSI-BLAST 26.221849 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glycerol transmembrane transporter activity
    		•  7.11654923455995 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • glycerol-3-phosphate transmembrane transporter activity
    		•  5.74077413704789 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.21476253433572 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  2.9533201822002 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  2.63293544825311 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • sugar binding
    		•  0.285073104957756 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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