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View Structure Prediction Details

Protein: itr2
Organism: Schizosaccharomyces pombe
Length: 557 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for itr2.

Description E-value Query
Range
Subject
Range
gi|49651677 - gi|49651677|emb|CAG78618.1| YALI0F23903p [Yarrowia lipolytica]
gi|50556798, gi|... - gi|50556798|ref|XP_505807.1| YALI0F23903p [Yarrowia lipolytica], gi|49651677|emb|CAG78618.1| unnamed...
247.0 [0..55] [552..31]
gi|190407247 - gi|190407247|gb|EDV10514.1| myo-inositol transporter [Saccharomyces cerevisiae RM11-1a]
ITR2_YEAST - Myo-inositol transporter 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ITR2 PE=1 SV=...
ITR2 - Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member ...
gi|151945530 - gi|151945530|gb|EDN63771.1| myo-inositol transporter [Saccharomyces cerevisiae YJM789]
241.0 [0..6] [556..33]
gi|50290281, gi|... - gi|50290281|ref|XP_447572.1| hypothetical protein CAGL0I07447g [Candida glabrata CBS138], gi|4952688...
gi|49526882 - gi|49526882|emb|CAG60509.1| unnamed protein product [Candida glabrata]
239.0 [0..17] [555..9]
gi|58269662, gi|... - gi|58269662|ref|XP_571987.1| myo-inositol transporter 2 [Cryptococcus neoformans var. neoformans JEC...
236.0 [0..8] [552..24]
gi|91078244 - gi|91078244|ref|XP_970364.1| PREDICTED: similar to CG10960-PB, isoform B [Tribolium castaneum]
235.0 [0..13] [536..620]
gi|50256832, gi|... - gi|50256832|gb|EAL19550.1| hypothetical protein CNBG1790 [Cryptococcus neoformans var. neoformans B-...
234.0 [0..8] [552..24]

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Predicted Domain #1
Region A:
Residues: [1-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFNNIPLAT IKSSDDKGKD FIVEMTTRPS ETKKKVPFSE DMREIPSLPN EEEANATDPQ  60
   61 ANEVADENGE GFEAEKISSW IWVLSAVAGI SGLLFGYDTG VISGALAVLG SDLGHVLSSG 120
  121 QKELITSATS FAALISATTS GWLADWVGRK RLLLCADAIF VIGSVIMAAS RNVAMMVVGR 180
  181 FIVGYGIGLT SLIVPMYITE LAPARLRGRL VIIYVVFITG GQLIAYSLNA AFEHVHQGWR 240
  241 IMFGIGAAPA LGQLISLFWT PESPRYLLRH NHVEKVYKIL SRIHPEAKPA EIAYKVSLIQ 300
  301 EGVKVDFPEG NKFQHFFHSL KVLFTVPSNR RSLFIGCFLQ WFQQFSGTNA IQYFSAIIFQ 360
  361 SVGFKNSISV SIVVGATNFV FTIVAFMFID RIGRRRILLC TSAVMIAGLA LCAIAYHFLP 420
  421 ADTTQNTNSG WQYVVLASII IFLASYASGI GNIPWQQAEL FPMEVRALGA GFSTAINWVG 480
  481 NLIISASFLT MMESITPTGT FALFAGFCFV GLVTSYFTYP ELAGMSIENI HKLLEKGFWQ 540
  541 AVKESTKRVR KGRIDEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.221849
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycerol transmembrane transporter activity 7.11654923455995 bayes_pls_golite062009
alcohol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
polyol transmembrane transporter activity 6.7545566917184 bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity 5.74077413704789 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.94605227012838 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 3.3746965264994 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 3.21476253433572 bayes_pls_golite062009
sugar:hydrogen symporter activity 2.99050613058546 bayes_pls_golite062009
cation:sugar symporter activity 2.99050613058546 bayes_pls_golite062009
phosphate transmembrane transporter activity 2.9533201822002 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 2.63293544825311 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.62141276633776 bayes_pls_golite062009
sugar transmembrane transporter activity 2.47557586092261 bayes_pls_golite062009
solute:hydrogen symporter activity 2.10485633822652 bayes_pls_golite062009
binding 1.89539096965643 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
sugar binding 0.285073104957756 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle