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Protein Overview: int6

General Information:
Name(s) found: int6 / SPBC646.09c [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • translation initiation factor eIF3e [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 501 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    eukaryotic 43S preinitiation complex [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    eukaryotic translation initiation factor 3 complex [TAS]
    Biological Process: ascospore formation [IMPLink to PubMed article]
    positive regulation of translational initiation [IC]
    eukaryotic translation initiation factor 3 complex assembly [IMPLink to PubMed article]
    proteasomal ubiquitin-dependent protein catabolic process [IGILink to PubMed article]
    protein complex assembly [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    response to caffeine [IMPLink to PubMed article]
    proteasome localization [IMPLink to PubMed article]
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IMPLink to PubMed article]
    proteasome assembly [IMPLink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    translation [IEA]
    Molecular Function: translation initiation factor activity [IEA]
    protein binding [IPILink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSELKSTSP LAVKYDLSQK IMQHLDRHLI FPLLEFLSLR QTHDPKELLQ AKYDLLKDTN  60
   61 MTDYVANLWT NLHGGHTDED MANAFAEKRR SVLQELSELE EEVQGILGVL ENPDLIAALR 120
  121 QDKGQNLQHL QEHYNITPER IAVLYKFAQF QYNCGNYGGA SDLLYHFRAF SKDPELNASA 180
  181 TWGKFASEIL TVDWDGAMEE LGKLREMVDS KSFKDSAVQL RNRTWLLHWS LFPLFNHANG 240
  241 CDTLCDLFFY TPYLNTIQTS CPWLLRYLTV AVVTNQNNAN QKPRNPRQSY QRRMRDLVRI 300
  301 ISQENYEYSD PVTSFISALY TEVDFEKAQH CLRECEEVLK TDFFLVSLCD HFLEGARKLL 360
  361 AEAYCRIHSV ISVDVLANKL EMDSAQLIQL VENRNNPSVA AASNVAADQS TEDESIESTS 420
  421 TNVVADDLIT EAETATEAEE PEPEVQFGFK AKLDGESIII EHPTYSAFQQ IIDRTKSLSF 480
  481 ESQNLEQSLA KSISELKHAT V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..149] Pfam 80.958607 No description for PF09440.1 was found. No confident structure predictions are available.
    2 View Details [150..282] MSA 2.033991 View MSA. No confident structure predictions are available.
    3 View Details [283..360] deduced N/A No confident structure predictions are available.
    4 View Details [361..501] FFAS03 3.17 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  3.40627040093952 bayes_pls_golite062009
  • DNA binding
    		•  3.18517869180019 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.974370828939 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.8293727459515 bayes_pls_golite062009
  • binding
    		•  2.73671056234733 bayes_pls_golite062009
  • structural molecule activity
    		•  2.72616711594099 bayes_pls_golite062009
  • transcription factor activity
    		•  2.51227631362049 bayes_pls_golite062009
  • transcription activator activity
    		•  2.04243540203739 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.96901349910727 bayes_pls_golite062009
  • protein binding
    		•  1.77689943618029 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.811726311475138 bayes_pls_golite062009
  • RNA binding
    		•  0.352569950847387 bayes_pls_golite062009
  • hydrolase activity
    		•  0.20695163916851 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.142921675412538 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.124542865343065 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle