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Protein Overview: SPAC56F8.03

General Information:
Name(s) found: SPAC56F8.03 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • translation initiation factor IF2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1079 amino acids

    Gene Ontology:
    Cellular Component: cytosolic small ribosomal subunit [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: positive regulation of translational initiation [ICLink to PubMed article]
    translational initiation [ISSLink to PubMed article]
    Molecular Function: GTP binding [ICLink to PubMed article]
    translation initiation factor activity [ISSLink to PubMed article]
    GTPase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKGKKSGY ADWEDDLGED ISGQNEYLDN TSQDSPQNDE LAEKSENLAV SSEKTTSKKK  60
   61 KGKKNKGNKN QVSDDESQEL ESPQGPKELT AVTELDDDEF DYKPKKGKKG KKSKKVEEDD 120
  121 EPQEIESPQG PKELTAVTEL DDDEFDYKPK KGKKGKKAQN NNESEAAAPP EIPEVRVKTK 180
  181 KEKEREKKER EKLRKKQQQA KKKGSTGEDT LASSEVSSEV DISTPAENDS SAKGKQAAGS 240
  241 KRKGPNVTAL QKMLEEKRAR EEEEQRIREE EARIAEEEKR LAEVEEARKE EARLKKKEKE 300
  301 RKKKEEMKAQ GKYLSKKQKE QQALAQRRLQ QMLESGVRVA GLSNGEKKQK PVYTNKKKSN 360
  361 RSGTSSISSS GILESSPATS ISVDEPQKDS KDDSEKVEKE TEVERKEENE AEAEAVFDDW 420
  421 EAALEEPEVA ENNEVVTEKK ETDIKSDAVE HSIKDKEDSK TDKVDDIPQA APAESNVSES 480
  481 DLRSPICCIL GHVDTGKTKL LDNLRRSNVQ EGEAGGITQQ IGATYFPIES IKQKTKVVNK 540
  541 KGKLQYNIPG LLIIDTPGHE SFTNLRSRGT SLCNIAILVI DIMHGLEPQT IESIRLLRDQ 600
  601 KTPFVVALNK VDRLYGWHSI KDNAIQDSLS KQKKAIQREF RDRVESIILQ LNEQGLNAAL 660
  661 YFENKNLGRY VSLVPTSAQS GEGVPDLVAL LISLTQTRMS DRIKYITTLE CTVLEVKVIE 720
  721 GLGATIDVIL SNGVLHEGDR IVLCGMGGPI ITTVRALLTP QPLKEMRVKS AYVHHKEIKA 780
  781 AMGVKICAND LEKAVAGSRL LVVGPDDDEE DLAEEIMEDL ENLLGRIDTS GIGVSVQAST 840
  841 LGSLEALLEF LKQMKIPVAS VNIGPVYKKD VMRCATMLEK AKEYALMLCF DVKVDRDAED 900
  901 LAEQLGVKIF SANVIYHLFD AFTAHQKKIL EQKREESSDV AVFPCVLKTV AAFNKRDPII 960
  961 LGVDVVEGVL RINTPIVAVK QLPNGEPQII ELGRVASLEM NHKPVDKVKK GQAGAGVAMK1020
 1021 LESSGSQILF GRQVTESDAL YSHITRQSID SLKDPAFRDE VSRDEWQLII QLKKLFGII

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..298] PSI-BLAST 6.154902 Heavy meromyosin subfragment
    2 View Details [299..476] FFAS03 0.971 crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
    3 View Details [477..1079] PSI-BLAST 78.522879 Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • translation initiation factor activity
    		•  5.88857268461955 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  5.41178688428159 bayes_pls_golite062009
  • structural molecule activity
    		•  4.44501073718522 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.02680549811636 bayes_pls_golite062009
  • binding
    		•  1.8340549733034 bayes_pls_golite062009
  • translation regulator activity
    		•  1.62528736558737 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.60662288414996 bayes_pls_golite062009
  • DNA binding
    		•  1.19966224604123 bayes_pls_golite062009
  • motor activity
    		•  1.14667913749579 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.09075553688438 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • protein binding
    		•  0.871734119777931 bayes_pls_golite062009
  • peptidyltransferase activity
    		•  0.696276842950831 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.60036517876321 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.569910969126728 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.568840867400671 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.568779924702229 bayes_pls_golite062009
  • nucleotide binding
    		•  0.564275755355315 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.500462538667228 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.2302541318658 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009
  • RNA binding
    		•  0.0693163519626152 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0612932659603008 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0530667986761242 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0482442222493492 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.028470639373934 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0265151533232588 bayes_pls_golite062009
  • actin binding
    		•  0.00482938540552702 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle