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Protein Overview: idp1

General Information:
Name(s) found: idp1 / SPAC6G10.08 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • isocitrate dehydrogenase Idp1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 418 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: glutamate biosynthetic process [ISSLink to PubMed article]
    isocitrate metabolic process [ISSLink to PubMed article]
    NADPH regeneration [ISS]
    tricarboxylic acid cycle [ICLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    NAD or NADH binding [IEA]
    isocitrate dehydrogenase (NADP+) activity [ISSLink to PubMed article]
    manganese ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMRMASSKS FQKITVKNPV VEMDGDEMTR VIWKIIREKL VLPYMDIKLD YYDLGIEARD  60
   61 KTNDQITVDA AKAILKNDVG IKCATITPDE ARVKEYNLKK MWKSPNGTIR NILNGTVFRE 120
  121 PILIKNIPKY IPGWTNPICI GRHAFGDQYK STDLVASGPG KLELSFTPKG NPSAKETYNV 180
  181 YEFNGSGVAM SMYNTDDSIR GFAHSSFQMA LQKKMPLYLS TKNTILKKYD GRFKDTFQEV 240
  241 YESDYKQKFE ELGLWYQHRL IDDMVAQAIK SNGGFVWACK NYDGDVMSDV VAQAYGSLGL 300
  301 MTSVLIHPNG RTFESEAAHG TVQRHYMQYL KGKKTSTNSI ASIFAWTRGL AHRGRLDGNE 360
  361 RLVKFANALE HACVRCVEKG IMTKDLYLLS KSPNGYVDTF EFLDAVKSEL DSELVNIA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..418] PSI-BLAST 125.0 NADP-dependent isocitrate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • isocitrate dehydrogenase (NAD+) activity
    		•  5.9567768649084 bayes_pls_golite062009
  • isocitrate dehydrogenase activity
    		•  5.76817846591752 bayes_pls_golite062009
  • isocitrate dehydrogenase (NADP+) activity
    		•  3.47645456015586 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.74237430402883 bayes_pls_golite062009
  • catalytic activity
    		•  2.71251959637136 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.46799258909805 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  2.38235863668553 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.15484868227001 bayes_pls_golite062009
  • 3-isopropylmalate dehydrogenase activity
    		•  0.848289435089509 bayes_pls_golite062009
  • binding
    		•  0.530580225668688 bayes_pls_golite062009
  • protein binding
    		•  0.074256700284446 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle