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A metabolic process by which a pool of NADPH generated by the reduction of NADP+. The process by which NADP+ is reduced to NADPH. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions. The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH. The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide. The process by which glucose is oxidized, coupled to NADPH synthesis. Glucose 6-P is oxidized with the formation of carbon dioxide (CO2), ribulose 5-phosphate and reduced NADP; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: NADPH regeneration
Acc: GO:0006740
Aspect: Biological Process
Desc: A metabolic process by which a pool of NADPH generated by the reduction of NADP+.
Synonyms:
  • reduced NADP regeneration
  • reduced nicotinamide adenine dinucleotide phosphate regeneration
  • NADP (reduced) regeneration
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 187 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006740 - NADPH regeneration (interactive image map)

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