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Protein Overview: hsf1

General Information:
Name(s) found: hsf1 / SPAC2E12.02 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • transcription factor Hsf1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 609 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: cellular response to stress [IDALink to PubMed article]
    regulation of transcription [ICLink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    Molecular Function: transcription factor activity [IDALink to PubMed article]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIQTASTISS NGGTNQGMES SSANSPEMNG TQNSMSVGMS GSGSSQNRKI TQFSNKLYNM  60
   61 VNDSSTDSLI RWSDRGDSFL VIGHEDFAKL VLPRYFKHNN FSSFVRQLNM YGFHKVPHIQ 120
  121 QGVLQSDSPN ELLEFANPNF QRDQPELLCL VTRKKAGSQP VEESNTSLDM STISSELQNI 180
  181 RIQQMNLSNE LSRIQVDNAA LWQENMENRE RQRRHQETID KILRFLASVY LDGKQKPPSK 240
  241 VMPKSRRLLL EAKYPTVSPT NEPSAHSRPS PQGTTANSSS ASISSLHNTT PDGEGKYRSV 300
  301 QNGRALNYVS SFNSDSHSPK DYISQSYTNE PGLKKESADS FNNSIDSYIS PNQSPNTDVP 360
  361 SLNRDDTTDP KVVNTGDIIN MLDDANSIEG SNMNSLSPLL FDYPNSLYPV NNTSSEQHHN 420
  421 SYRGSVSNSQ PSGNLSESTN LQPVQPVDYM SNSNPSYGSY NAEDQLTNFH PGYAMDQKRI 480
  481 SKLSDGITKQ DQNIQALADI LGIPLGDGKI DDAGFSANSP TNLNLPVSSD LDSVLNIPPN 540
  541 EDVFPDSNPV FDEFTNISNL TSPIEASNGN TFGSNPVSLP NQQKSVNPSL MTVSSPRQVR 600
  601 KKRKSSIGA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..156] PSI-BLAST 39.0 SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
    2 View Details [157..295] Pfam 9.167491 No description for PF00447.8 was found. No confident structure predictions are available.
    3 View Details [296..461] MSA 1.154994 View MSA. No confident structure predictions are available.
    4 View Details [462..609] MSA 2.053994 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.77201910025409 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • DNA binding
    		•  3.44642410378325 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.25777282180864 bayes_pls_golite062009
  • transcription factor activity
    		•  2.83460075788873 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.39237599101586 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.4788427609721 bayes_pls_golite062009
  • transcription activator activity
    		•  1.28486271107855 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • transcription factor binding
    		•  0.63938506997853 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.49916895549368 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.359916369552683 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.0565989703351002 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle