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Protein Overview: tms1

General Information:
Name(s) found: tms1 / SPBC1773.05c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • hexitol dehydrogenase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 360 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: hexitol catabolic process [ICLink to PubMed article]
    cellular response to stress [IEPLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    L-iditol 2-dehydrogenase activity [ISSLink to PubMed article]
    D-xylulose reductase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPAEKAFVL RKKMDTAIED RPGQTLTDDH QVKVAIKATG ICGSDVHYWK EGGIGDFILK  60
   61 KPMILGHESA GVVVEVGKGV SSLKPGDPVA VEPGCVCRLC DYCRSGRYNL CPHMEFAATP 120
  121 PYDGTLRTYY ITTEDFCTKL PKQISVEEGA LFEPMSVAVH AMTRGNLKCG SRVLVMGCGT 180
  181 VGLLMMAVAK AYGAIDIVAV DASPSRVEFA QKYVGAKPFT PIAAKENESL PDYAQRYKQA 240
  241 IIEKYGEFDF AVDATGVGIC IHTAVLALKR GGTFVQAGNG KPVIDFPINH IINYEINVLG 300
  301 SFRYAHGCYK QSLFLVSNGL VDVKPLITHR FAFKDALKAY ETVASGEEGV LKVIIGGPDA 360
  361

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..360] PSI-BLAST 81.09691 Ketose reductase (sorbitol dehydrogenase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ethanol binding
    		•  4.47659026306883 bayes_pls_golite062009
  • NAD or NADH binding
    		•  4.35058438816264 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  4.1750549780559 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • L-iditol 2-dehydrogenase activity
    		•  3.00103406168296 bayes_pls_golite062009
  • alcohol binding
    		•  2.97042200128883 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  2.94416173750168 bayes_pls_golite062009
  • retinol binding
    		•  2.89007863838685 bayes_pls_golite062009
  • all-trans retinal binding
    		•  2.84803957533249 bayes_pls_golite062009
  • S-(hydroxymethyl)glutathione dehydrogenase activity
    		•  2.58673703881996 bayes_pls_golite062009
  • hydroxymethylfurfural reductase activity
    		•  2.2999175117758 bayes_pls_golite062009
  • hydroxymethylfurfural reductase (NADH) activity
    		•  2.2999175117758 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  2.26153457113968 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  2.16668841986245 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.03039843216597 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  1.38219425408212 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  1.29842732066898 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  1.07006097264025 bayes_pls_golite062009
  • chaperone binding
    		•  1.04678886151518 bayes_pls_golite062009
  • retinoid binding
    		•  1.04593455330515 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.01627645289834 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.93398178725124 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.527946013169731 bayes_pls_golite062009
  • hydrolase activity
    		•  0.41684292392606 bayes_pls_golite062009
  • hydroxymethylfurfural reductase (NADPH) activity
    		•  0.382131941157781 bayes_pls_golite062009
  • L-arabinitol 2-dehydrogenase activity
    		•  0.382131941157781 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
    		•  0.361275519814065 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • binding
    		•  0.355184540089764 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  0.320177384202291 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase activity
    		•  0.298691872199351 bayes_pls_golite062009
  • ATPase activity
    		•  0.275256680720412 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  0.250698007650211 bayes_pls_golite062009
  • methylenetetrahydrofolate dehydrogenase activity
    		•  0.169301675015808 bayes_pls_golite062009
  • methenyltetrahydrofolate cyclohydrolase activity
    		•  0.162625185692811 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.0962368786590111 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.63

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle